2-Hydroxyethyl 2-bromo-2-methylpropanoate;hydrobromide

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: 2-Hydroxyethyl 2-bromo-2-methylpropanoate;hydrobromide
• 英文别名: 2-hydroxyethyl 2-bromo-2-methylpropanoate;hydrobromide
• 化学式: C6H12Br2O3
• 分子量: 291.97
• InChiKey: BQTNHEDUSTZKDQ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.27
• 重原子数：
  11
• 可旋转键数：
  4
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.83
• 拓扑面积：
  46.5
• 氢给体数：
  2
• 氢受体数：
  3

文献信息

• Atom transfer radical polymerization under biologically compatible conditions
  申请人：Carnegie Mellon University

  公开号：US10072042B2

  公开（公告）日：2018-09-11

  Methods for conducting controlled grafting-from radical polymerizations from biomolecules under conditions that are biologically compatible are described. The methods provide biomolecule-polymer conjugates with highly controlled structures and narrow polydispersities under aqueous reaction conditions and biological temperatures. Biomolecules, such as proteins and nucleotides can be conjugated to polymers with high levels of control.

  本文介绍了在与生物相容的条件下对生物大分子进行受控接枝-自由基聚合的方法。这些方法提供了在水反应条件和生物温度下结构高度受控、聚分散性较窄的生物分子-聚合物共轭物。蛋白质和核苷酸等生物大分子可与聚合物高度可控地共轭。
• US20140275420A1
  申请人：——

  公开号：US20140275420A1

  公开（公告）日：2014-09-18
• ATOM TRANSFER RADICAL POLYMERIZATION UNDER BIOLOGICALLY COMPATIBLE CONDITIONS
  申请人：Carnegie Mellon University

  公开号：US20170145048A1

  公开（公告）日：2017-05-25

  Methods for conducting controlled grafting-from radical polymerizations from biomolecules under conditions that are biologically compatible are described. The methods provide biomolecule-polymer conjugates with highly controlled structures and narrow polydispersities under aqueous reaction conditions and biological temperatures. Biomolecules, such as proteins and nucleotides can be conjugated to polymers with high levels of control.