2-[(E)-1-bromoprop-1-enyl]-3-ethenyl-1H-pyrrole

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡咯
• 英文名称: 2-[(E)-1-bromoprop-1-enyl]-3-ethenyl-1H-pyrrole
• 化学式: C₉H₁₀BrN
• 分子量: 212.09
• InChiKey: SIMVKBUDEYIZSJ-XBXARRHUSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3
• 重原子数：
  11
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.11
• 拓扑面积：
  15.8
• 氢给体数：
  1
• 氢受体数：
  0

文献信息

• COMPOUNDS AND METHODS FOR TREATING CANCERS
  申请人：HEALTH RESEARCH, INC.

  公开号：US20160368872A1

  公开（公告）日：2016-12-22

  Provided are carbazole and carbazole-like compounds (e.g., pyridoindole and pyrrolodipyridine compounds. The compounds can be used to selectively kill cancer cells. Prostate cancer (PCa) is the most frequent neoplastic disease and the second leading cause of cancer-related deaths in men, claiming more than 30,000 men each year in the United States alone. PCa tumors are composed primarily of prostate luminal epithelial cells. Differentiation of prostate luminal epithelial cells is controlled in part by Androgen receptor (AR) driven expression of prostate-specific markers.
• [EN] COMPOUNDS AND METHODS FOR TREATING CANCERS<br/>[FR] COMPOSÉS ET MÉTHODES DE TRAITEMENT DE CANCERS
  申请人：HEALTH RESEARCH INC

  公开号：WO2014153055A2

  公开（公告）日：2014-09-25

  Provided are carbazole and carbazole-like compounds (e.g., pyridoindole and pyrrolodipyridine compounds. The compounds can be used to selectively kill cancer cells.