methyl 2-[(5E)-5-[[5-(4-methyl-3-nitrophenyl)furan-2-yl]methylidene]-2,4-dioxo-1,3-thiazolidin-3-yl]propanoate

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: methyl 2-[(5E)-5-[[5-(4-methyl-3-nitrophenyl)furan-2-yl]methylidene]-2,4-dioxo-1,3-thiazolidin-3-yl]propanoate
• 化学式: C19H16N2O7S
• 分子量: 416.4
• InChiKey: SSVVSVVKQFARCB-CXUHLZMHSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.7
• 重原子数：
  29
• 可旋转键数：
  5
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.21
• 拓扑面积：
  148
• 氢给体数：
  0
• 氢受体数：
  8

文献信息

• Methods of modulating neurotrophin-mediated activity
  申请人：Ross M. Gregory

  公开号：US20050282840A1

  公开（公告）日：2005-12-22

  Disclosed are compositions which modulate the interaction of nerve growth factor and brain-derived neurotrophic factor with neurotrophic receptors. Also disclosed are methods of using the compositions of the invention, including methods of administration.

  本发明揭示了一种调节神经生长因子和脑源性神经营养因子与神经营养受体相互作用的组合物。还揭示了使用该发明的组合物的方法，包括给药方法。
• Process for the living radical polymerization of chlorine containing monomers
  申请人：UNIVERSITY OF PENNSYLVANIA

  公开号：US20020173611A1

  公开（公告）日：2002-11-21

  A process for the preparation of polyvinyl chloride (PVC) with controlled molecular weight and molecular weight distribution is disclosed. The polymerization reaction can be initiated by various organic halide initiators in conjunction with a metal catalyst and an optional ligand in organic solvents or water and in the presence of an optional comonomer. The polymerization process provides PVC with a controlled molecular weight and narrow molecular weight distribution. The chlorine containing polymers compositions are useful as, among others, viscosity modifiers, impact modifiers and compatibilizers.

  本发明公开了一种制备具有可控分子量和分子量分布的聚氯乙烯（PVC）的工艺。聚合反应可由各种有机卤化物引发剂与金属催化剂和任选配体在有机溶剂或水中并在任选共聚单体的存在下引发。聚合过程可提供分子量可控、分子量分布窄的聚氯乙烯。含氯聚合物组合物可用作粘度调节剂、抗冲击调节剂和相容剂等。
• EP1718308A4
  申请人：——

  公开号：EP1718308A4

  公开（公告）日：2007-07-18
• METHODS OF MODULATING NEUROTROPHIN-MEDIATED ACTIVITY
  申请人：PainCeptor Pharma Corp.

  公开号：EP1718308A2

  公开（公告）日：2006-11-08
• US6838535B2
  申请人：——

  公开号：US6838535B2

  公开（公告）日：2005-01-04