(2R)-1-(4,4,7-trimethylindeno[1,2-b]pyrrol-1-yl)propan-2-amine

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡咯
• 英文名称: (2R)-1-(4,4,7-trimethylindeno[1,2-b]pyrrol-1-yl)propan-2-amine
• 化学式: C₁₇H₂₂N₂
• 分子量: 254.37
• InChiKey: IPIHGDDHIVDPOJ-GFCCVEGCSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3
• 重原子数：
  19
• 可旋转键数：
  2
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.41
• 拓扑面积：
  31
• 氢给体数：
  1
• 氢受体数：
  1

文献信息

• Preventives/Remedies for Stress Urinary Incontinence and Method of Screening the Same
  申请人：Kamo Izumi

  公开号：US20070274913A1

  公开（公告）日：2007-11-29

  An agent for the prophylaxis or treatment of stress urinary incontinence, which contains a substance that activates a serotonin 5-HT 2C receptor, an agent for the prophylaxis or treatment of stress urinary incontinence, which contains a substance that stimulates an androgen binding site, and a method of screening for a drug for the prophylaxis or treatment of abdominal pressure incontinence, which includes electrostimulating the abdominal muscles or a nerve controlling them of an animal to increase the abdominal pressure, and measuring the leak point pressure at that time.