calcium;(2S)-2-(hydroxymethylamino)-4-methylsulfanylbutanoate

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: calcium;(2S)-2-(hydroxymethylamino)-4-methylsulfanylbutanoate
• 化学式: C12H24CaN2O6S2
• 分子量: 396.5
• InChiKey: NWNPLGLJNZEMTE-MDTVQASCSA-L

计算性质

• 辛醇/水分配系数(LogP)：
  -3.59
• 重原子数：
  23
• 可旋转键数：
  10
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.83
• 拓扑面积：
  195
• 氢给体数：
  4
• 氢受体数：
  10

文献信息

• An additive composition for ruminant feed
  申请人：Ajinomoto Co., Inc.

  公开号：EP0678246A1

  公开（公告）日：1995-10-25

  A granular additive composition for ruminant feed which stably protects the biologically active substance in the rumen of the ruminant and allows it to be effectively digested and absorbed in the digestive organs after the abomasum is provided with consideration of safety and economy. This granular additive composition for ruminant feed comprises a core comprising a biologically active substance and a coating composition coated thereon, said coating composition comprising 90 to 68 % by weight of (A) at least one hydrophobic protecting substance selected from the group consisting of hardened animal and plant oil and fat, an animal and plant fat, and a fatty acid ester, 2 to 10 % by weight of (B) a surface active agent compatible with said hydrophobic protecting substance (A), and 8 to 30 % by weight of (C) talc powder. The granular additive composition simultaneously has excellent protecting property in the rumen of the ruminant and extremely excellent releasability in the digestive organs after the abomasum.

  考虑到安全性和经济性，提供了一种反刍动物饲料颗粒添加剂组合物，它能在反刍动物的瘤胃中稳定地保护生物活性物质，并使其在瘤胃后的消化器官中被有效消化和吸收。 这种用于反刍动物饲料的颗粒状添加剂组合物包括由生物活性物质组成的核心和涂覆在其上的包衣组合物，所述包衣组合物包括 90% 至 68% （重量百分比）的（A）至少一种疏水保护物质，该物质选自由硬化的动植物油脂、动植物脂肪和脂肪酸酯组成的组、 以重量计，2%至 10%的(B)与所述疏水保护物质(A)相容的表面活性剂，以及 8-30 %（重量百分比）的（C）滑石粉。 这种颗粒状添加剂组合物在反刍动物的瘤胃中同时具有极佳的保护性能，在腹腔后的消化器官中具有极佳的释放性。
• Method of growing bacteria to deliver bioactive compounds to the intestine of ruminants
  申请人：Sage Biosciences Inc.

  公开号：EP2311937A1

  公开（公告）日：2011-04-20

  Methods for increasing the resistance to rumen inactivation of a cultured Gram positive bacteria strain useful for gastrointestinal delivery of bioactive compounds to ruminants, which includes the steps of growing a culture of the bacteria strain through at least one passage in a growth medium containing an amount of lysozyme effective to induce the growth of bacterial cell walls resistant to protozoal predation; and recovering the bacteria strain from the lysozyme-containing medium. Rumen-bypass feed supplements produced by the inventive method are also disclosed, as well as methods for supplementing the diet of a ruminant with the rumen bypass feed supplements and an in vitro method for evaluating the resistance of Gram positive bacteria strains to rumen inactivation in vivo.

  提高用于向反刍动物胃肠道输送生物活性化合物的培养革兰氏阳性菌菌株的抗瘤胃灭活能力的方法，包括以下步骤：在含有一定量溶菌酶的生长培养基中培养至少一个菌株，该培养基能有效诱导抗原生动物捕食的细菌细胞壁生长；以及从含溶菌酶的培养基中回收菌株。本发明还公开了用本发明方法生产的瘤胃旁路饲料补充剂，以及用瘤胃旁路饲料补充剂补充反刍动物饮食的方法和评估革兰氏阳性菌菌株对体内瘤胃灭活的抗性的体外方法。
• Granular feed supplement
  申请人：Wright Danny R.

  公开号：US10092533B2

  公开（公告）日：2018-10-09

  A ruminant feed composition, having a granulated core having at least one active substance and at least one layer of a coating material surrounding the core, the coating material comprising one or more linear, saturated aliphatic monocarboxylic acids in an amount of at least 60 wt % of the total weight of the coating material.

  一种反刍动物饲料组合物，其颗粒核心含有至少一种活性物质，核心周围有至少一层涂层材料，涂层材料包括一种或多种线性饱和脂肪族一元羧酸，其含量至少占涂层材料总重量的 60%。
• Feed additive for ruminants
  申请人：MITSUBISHI KASEI CORPORATION

  公开号：EP0351760B1

  公开（公告）日：1994-12-28
• Rieselfähige Methionin-haltige Formlinge und Verfahren zu deren Herstellung
  申请人：Degussa GmbH

  公开号：EP0992490B2

  公开（公告）日：2007-08-29