N,2,2-trifluoro-2-nitro-N-phenylacetamide

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: N,2,2-trifluoro-2-nitro-N-phenylacetamide
• 化学式: C8H5F3N2O3
• 分子量: 234.13
• InChiKey: HVHSBFUTMXLGQO-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.4
• 重原子数：
  16
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.12
• 拓扑面积：
  66.1
• 氢给体数：
  0
• 氢受体数：
  6

文献信息

• COMPOSITIONS AND METHODS FOR DETECTING ALBUMIN
  申请人：Tournament BioVenture LLC

  公开号：US20210156868A1

  公开（公告）日：2021-05-27

  The present disclosure provides a method for determining the amount of albumin in a sample. In one embodiment, the method involves treating the sample with an esterase inhibitor that selectively inhibits non-albumin esterase activity; combining the sample with a selective substrate of albumin, which has a carboxylic ester bond, so that the carboxylic ester bond is cleaved to generate a hydrolysate; detecting the amount of the hydrolysate generated in a period of time; and determining the amount of the albumin in the sample based on the amount of the hydrolysate in the period of time.