N-苯基亚胺磷酰三氯 | 5290-43-7

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 中文名称: N-苯基亚胺磷酰三氯
• 英文名称: Phenylimino-phosphortrichlorid
• 英文别名: phenyl-imidophosphoryl chloride；Phosphorsaeure-trichlorid-anil；N-Phenyliminophosphoric acid trichloride；trichloro(phenylimino)-λ5-phosphane
• CAS: 5290-43-7
• 化学式: C₆H₅Cl₃NP
• 分子量: 228.445
• InChiKey: VFZIWOHWFWEWML-UHFFFAOYSA-N

物化性质

• 熔点：
  172-178 °C
• 沸点：
  286.7±23.0 °C(Predicted)
• 密度：
  1.48±0.1 g/cm3(Predicted)
• 稳定性/保质期：

  避免与湿空气、水分直接接触，并且不要与强氧化剂反应。

计算性质

• 辛醇/水分配系数(LogP)：
  4.1
• 重原子数：
  11
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  12.4
• 氢给体数：
  0
• 氢受体数：
  1

安全信息

• 危险类别码：
  R34,R23/24/25
• 海关编码：
  2931900090
• 储存条件：
  密封保存，应储存在阴凉干燥的库房中，并远离腐蚀性物质。

SDS

Name:	N-Phenyliminophosphoric acid trichloride Material Safety Data Sheet
Synonym:
CAS:	5290-43-7

Section 1 - Chemical Product MSDS Name: N-Phenyliminophosphoric acid trichloride Material Safety Data Sheet
Synonym:

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SECTION 2 - COMPOSITION, INFORMATION ON INGREDIENTS

CAS#	Chemical Name	content	EINECS#
5290-43-7	N-Phenyliminophosphoric acid trichlori	100	unlisted

Hazard Symbols: T C
Risk Phrases: 23/24/25 34

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SECTION 3 - HAZARDS IDENTIFICATION EMERGENCY OVERVIEW Toxic by inhalation, in contact with skin and if swallowed. Causes burns.Corrosive.Moisture sensitive.The toxicological properties of this material have not been fully investigated. Potential Health Effects
Eye:
Causes eye burns.
Skin:
Harmful if absorbed through the skin. Causes skin burns.
Ingestion:
Harmful if swallowed. May cause severe and permanent damage to the digestive tract. Causes gastrointestinal tract burns.
Inhalation:
Harmful if inhaled. Causes chemical burns to the respiratory tract.
Chronic:
No information found.

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SECTION 4 - FIRST AID MEASURES
Eyes:
Get medical aid immediately. Do NOT allow victim to rub eyes or keep eyes closed. Extensive irrigation with water is required (at least 30 minutes).
Skin:
Get medical aid immediately. Immediately flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse. Destroy contaminated shoes.
Ingestion:
Do not induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately.
Inhalation:
Get medical aid immediately. Remove from exposure and move to fresh air immediately. If breathing is difficult, give oxygen. Do NOT use mouth-to-mouth resuscitation. If breathing has ceased apply artificial respiration using oxygen and a suitable mechanical device such as a bag and a mask.
Notes to Physician:

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SECTION 5 - FIRE FIGHTING MEASURES
General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion.
Extinguishing Media:
Use extinguishing media most appropriate for the surrounding fire. Do NOT get water inside containers. Use water spray, dry chemical, carbon dioxide, or appropriate foam.

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SECTION 6 - ACCIDENTAL RELEASE MEASURES
General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Vacuum or sweep up material and place into a suitable disposal container. Clean up spills immediately, observing precautions in the Protective Equipment section. Avoid generating dusty conditions. Provide ventilation. Do not get water inside containers.

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SECTION 7 - HANDLING and STORAGE
Handling:
Minimize dust generation and accumulation. Keep container tightly closed. Do not get on skin or in eyes. Do not ingest or inhale. Do not allow contact with water. Use only in a chemical fume hood. Discard contaminated shoes. Keep from contact with moist air and steam.
Storage:
Keep container closed when not in use. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Corrosives area. Store protected from moisture.

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SECTION 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
Engineering Controls:
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low. Exposure Limits CAS# 5290-43-7: Personal Protective Equipment
Eyes:
Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to minimize contact with skin.
Respirators:
A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant respirator use.

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SECTION 9 - PHYSICAL AND CHEMICAL PROPERTIES
Physical State: Solid
Color: Not available.
Odor: Irritating odor
pH: Not available.
Vapor Pressure: Not available.
Viscosity: Not available.
Boiling Point: Not available.
Freezing/Melting Point: 172 - 178 deg C
Autoignition Temperature: Not available.
Flash Point: Not available.
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature:
Solubility in water: soluble in chloroform, acetone
Specific Gravity/Density:
Molecular Formula: C6H5Cl3NP
Molecular Weight: 228.38

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SECTION 10 - STABILITY AND REACTIVITY
Chemical Stability:
Stable under normal temperatures and pressures. Moisture sensitive.
Conditions to Avoid:
Incompatible materials, dust generation, strong oxidants, exposure to moist air or water.
Incompatibilities with Other Materials:
Strong oxidizing agents.
Hazardous Decomposition Products:
Hydrogen chloride, carbon monoxide, oxides of nitrogen, carbon dioxide.
Hazardous Polymerization: Has not been reported.

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SECTION 11 - TOXICOLOGICAL INFORMATION RTECS#: CAS# 5290-43-7 unlisted.
LD50/LC50:
Not available.
Carcinogenicity:
N-Phenyliminophosphoric acid trichloride - Not listed by ACGIH, IARC, or NTP.

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SECTION 12 - ECOLOGICAL INFORMATION

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SECTION 13 - DISPOSAL CONSIDERATIONS Dispose of in a manner consistent with federal, state, and local regulations.

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SECTION 14 - TRANSPORT INFORMATION IATA
Shipping Name: CORROSIVE SOLID, TOXIC, N.O.S.
Hazard Class: 8 (6.1)
UN Number: 2923
Packing Group: III IMO
Shipping Name: CORROSIVE SOLID, TOXIC, N.O.S.
Hazard Class: 8 (6.1)
UN Number: 2923
Packing Group: III RID/ADR
Shipping Name: CORROSIVE SOLID, TOXIC, N.O.S.
Hazard Class: 8
UN Number: 2923
Packing group: III

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SECTION 15 - REGULATORY INFORMATION European/International Regulations European Labeling in Accordance with EC Directives
Hazard Symbols: T C
Risk Phrases:
R 23/24/25 Toxic by inhalation, in contact with skin and if swallowed. R 34 Causes burns.
Safety Phrases:
S 25 Avoid contact with eyes. S 28A After contact with skin, wash immediately with plenty of water. S 36/37/39 Wear suitable protective clothing, gloves and eye/face protection. S 45 In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible). WGK (Water Danger/Protection) CAS# 5290-43-7: No information available. Canada None of the chemicals in this product are listed on the DSL/NDSL list. CAS# 5290-43-7 is not listed on Canada's Ingredient Disclosure List. US FEDERAL TSCA CAS# 5290-43-7 is not listed on the TSCA inventory. It is for research and development use only.

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SECTION 16 - ADDITIONAL INFORMATION
MSDS Creation Date: 2/24/1999 Revision #2 Date: 3/18/2003 The information above is believed to be accurate and represents the best information currently available to us. However, we make no warranty of merchantability or any other warranty, express or implied, with respect to such information, and we assume no liability resulting from its use. Users should make their own investigations to determine the suitability of the information for their particular purposes. In no way shall the company be liable for any claims, losses, or damages of any third party or for lost profits or any special, indirect, incidental, consequential or exemplary damages, howsoever arising, even if the company has been advised of the possibility of such damages.

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SECTION 16 - ADDITIONAL INFORMATION
N/A

反应信息

• 作为反应物：
  描述：

  硫酸 、 N-苯基亚胺磷酰三氯 生成 盐酸 、 对氨基苯磺酸
  参考文献：
  名称：

  Gilpin, American Chemical Journal, 1897, vol. 19, p. 357

  摘要：

  DOI：
• 作为产物：
  描述：

  aniline hydrochloride 在 五氯化磷 作用下， 以 1,1,2,2-四氯乙烷 为溶剂， 生成 N-苯基亚胺磷酰三氯
  参考文献：
  名称：

  Catalytic Double-Bond Metathesis without the Transition Metal

  摘要：

  Iminophosphoranes of the type X3P=NR (X=Cl, pyrrolyl; R=alkyl, aryl) catalytically metathesize C=N bonds of carbodiimides via an addition/elimination mechanism that, despite the lack of d orbital participation in P-N bonding, conserves the key features of metal-catalyzed olefin metathesis. Diazaphosphetidine intermediates, produced by the formal [2+2] addition of carbodiimides to the P=N bond, have been isolated and characterized. All phosphorus-containing species in the complex catalytic reaction mixtures have been identified and their origins explained. The kinetics of addition of diisopropylcarbodiimide to Cl3P=NPl and subsequent elimination were studied, and rate constants were determined: k(add)=1.7x10(-3) (+/-0.1x10(-3)) M s(-1) and k(elim)=4.0x10(-4) (+/-0.3x10(-4)) s(-1). The rate of these reactions corresponds well with the observed catalytic TOF of 1.44 TO/P/h.

  DOI：

  10.1021/ja020494v