(NE)-N-(5-chloro-2,3-dihydroinden-1-ylidene)hydroxylamine

• 分子结构分类: 有机化合物 - 苯类化合物 - 茚满类
• 英文名称: (NE)-N-(5-chloro-2,3-dihydroinden-1-ylidene)hydroxylamine
• 化学式: C₉H₈ClNO
• 分子量: 181.62
• InChiKey: UQTIJEKCRQCDEK-PKNBQFBNSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.5
• 重原子数：
  12
• 可旋转键数：
  0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.22
• 拓扑面积：
  32.6
• 氢给体数：
  1
• 氢受体数：
  2

文献信息

• [EN] (FUSED RING ARYLAMINO AND HETEROCYCLYLAMINO) PYRIMIDYNYL AND 1,3,5-TRIAZINYL BENZIMIDAZOLES, PHARMACEUTICAL COMPOSITIONS THEREOF, AND THEIR USE IN TREATING PROLIFERATIVE DISEASES<br/>[FR] (ARYLAMINO ET HÉTÉROCYCLYLAMINO À CYCLE CONDENSÉ)PYRIMIDINYL- ET 1,3,5-TRIAZINYLBENZIMIDAZOLES, COMPOSITIONS PHARMACEUTIQUES DE CEUX-CI ET LEUR UTILISATION DANS LE TRAITEMENT DE MALADIES PROLIFÉRATIVES
  申请人：PATHWAY THERAPEUTICS INC

  公开号：WO2012135166A1

  公开（公告）日：2012-10-04

  Provided herein are (fused ring arylamino and heterocyclylamino) pyrimidinyl and 1,3,5-triazinyl benzimidazoles, e.g., a compound of Formula (I), and their pharmaceutical compositions, preparation, and use as agents or drugs for treating proliferative diseases.

  本文提供了（融合环芳基氨基和杂环基氨基）嘧啶基和1,3,5-三嗪基苯并咪唑化合物，例如公式（I）中的化合物，以及它们的制备方法、药物组成物和作为治疗增生性疾病的药物或制剂的用途。
• (FUSED RING ARYLAMINO AND HETEROCYCLYLAMINO) PYRIMIDINYL AND 1,3,5-TRIAZINYL BENZIMIDAZOLES, PHARMACEUTICAL COMPOSITIONS THEREOF, AND THEIR USE IN TREATING PROLIFERATIVE DISEASES
  申请人：Brown S. David

  公开号：US20140088103A1

  公开（公告）日：2014-03-27

  Provided herein are (fused ring arylamino and heterocyclylamino) pyrimidinyl and 1,3,5-triazinyl benzimidazoles, e.g., a compound of Formula (I), and their pharmaceutical compositions, preparation, and use as agents or drugs for treating proliferative diseases.

  本文提供了(fused ring arylamino和heterocyclylamino) pyrimidinyl和1,3,5-triazinyl benzimidazoles，例如，公式(I)的化合物及其制备方法、药物组合物和用于治疗增殖性疾病的药物。
• (FUSED RING ARYLAMINO AND HETEROCYCLYLAMINO) PYRIMIDYNYL AND 1,3,5-TRIAZINYL BENZIMIDAZOLES, PHARMACEUTICAL COMPOSITIONS THEREOF, AND THEIR USE IN TREATING PROLIFERATIVE DISEASES
  申请人：MEI Pharma, Inc.

  公开号：EP2691388A1

  公开（公告）日：2014-02-05
• US6737547B1
  申请人：——

  公开号：US6737547B1

  公开（公告）日：2004-05-18
• [EN] COMPOSITIONS CONTAINING AND METHODS OF USING N-ACYL-1H-AMINOINDENES<br/>[FR] COMPOSITIONS CONTENANT N-ACYL-1H-AMINOINDENES ET LEURS PROCEDES D'UTILISATION
  申请人：TEVA PHARMA

  公开号：WO2000038673A1

  公开（公告）日：2000-07-06

  The present invention provides novel aminoindenes having structure (1) wherein n is 1 or 2, R1 is hydrogen, linear or branched chain C¿1?-C8 alkyl or linear or branched chain C1-C8 alkoxy and R?2¿ is hydrogen or a halogen. Such compounds may be used to treat neurodegenerative conditions such as Alzheimer's disease, head trauma, stroke, hypoxia, anoxia, epilepsy, convulsions, and seizures.