N1,N2双(4-氟苯基)草酰胺 | 10197-51-0

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 中文名称: N1,N2双(4-氟苯基)草酰胺
• 英文名称: N¹,N²-bis(4-fluorophenyl)oxalamide
• 英文别名: N,N’-bis(4-fluorophenyl)oxamide；N,N'-bis(4-fluorophenyl)oxalamide；N,N'-bis(4-fluorophenyl)oxamide
• CAS: 10197-51-0
• 化学式: C₁₄H₁₀F₂N₂O₂
• 分子量: 276.242
• InChiKey: GNWMMQXKVPLTSP-UHFFFAOYSA-N

物化性质

• 密度：
  1.439±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  2.6
• 重原子数：
  20
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  58.2
• 氢给体数：
  2
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  N1,N2双(4-氟苯基)草酰胺 在 tetraphosphorus decasulfide 作用下， 以 xylene 为溶剂， 生成 N,N'-Bis-(4-fluoro-phenyl)-dithiooxalamide
  参考文献：
  名称：

  不对称二硫代草酰胺的制备。

  摘要：

  DOI：

  10.1021/jo01280a062
• 作为产物：
  描述：

  草酸二乙酯 、 4-氟苯胺 在 硼酸 作用下， 以 neat (no solvent) 为溶剂， 反应 2.0h， 生成 N1,N2双(4-氟苯基)草酰胺
  参考文献：
  名称：

  Iskra, Jernej; Titan, Primoz; Meglic, Vladimir, Acta Chimica Slovenica, 2013, vol. 60, # 3, p. 561 - 568

  摘要：

  DOI：

文献信息

• METHOD FOR CONVERTING HYDROXYL GROUP OF ALCOHOL
  申请人：Takasago International Corporation

  公开号：US20210047254A1

  公开（公告）日：2021-02-18

  The present invention relates to: a method for converting a hydroxyl group of an alcohol; and a catalyst which makes the method possible. A method for converting a hydroxyl group of an alcohol according to the present invention is characterized by producing a compound represented by CH(R 1 )(R 2 )Nu (wherein R 1 , R 2 and Nu are as defined below) by reacting an alcohol represented by CH(R 1 )(R 2 )OH (wherein each of R 1 and R 2 represents a hydrogen atom, an optionally substituted alkyl group, or the like) and a compound having an active proton, which is represented by H-Nu (wherein Nu represents a group represented by —CHX 1 -EWG 1 or —NR 3 R 4 ; X 1 represents a hydrogen atom or the like; EWG 1 represents an electron-withdrawing group; and each of R 3 and R 4 represents a hydrogen atom, an optionally substituted alkyl group, or the like), with each other in the presence of a complex of a group 7-11 metal of the periodic table and at least one solid base that is selected from the group consisting of layered double hydroxides, composite oxides and calcium hydroxide.

  本发明涉及：将醇的羟基转化为的方法；以及使该方法成为可能的催化剂。根据本发明的将醇的羟基转化为的方法的特征在于，在周期表的7-11族金属群的复合物存在下，通过将一个由CH(R1)(R2)OH（其中R1和R2分别表示氢原子、可选择取代的烷基基团或类似物）表示的醇与一个具有活性质子的化合物（其中Nu表示由—CHX1-EWG1或—NR3R4表示的基团；X1表示氢原子或类似物；EWG1表示电子吸引基团；R3和R4分别表示氢原子、可选择取代的烷基基团或类似物）反应，从而产生一个由CH(R1)(R2)Nu（其中R1、R2和Nu如下定义）表示的化合物。同时，所述反应中至少选择一种来自层状双氢氧化物、复合氧化物和氢氧化钙的固体碱作为催化剂。
• Bis(N,N′-substituted oxamate) Zincate(II) complexes: Synthesis, spectroscopy, solid state structure and DFT calculations
  作者：Deeb Taher、Firas F. Awwadi、Mousa Al-Noaimi、Lina K. Khader、Hassan K. Juwhari、Hazem Amarne、Mohammed H. Kailani、Abdellatif Ibdah

  DOI：10.1016/j.ica.2019.01.001

  日期：2019.3

  Abstract Treatment of two equivalents of N,N′-bis(X-phenyl)oxamides (1) with one equivalent of [Zn(OAc)2(H2O)2] (2) in the presence of four equivalents of [nBu4N]OH produce the corresponding bis(N,N′-substituted oxamate) zincate(II) complexes with the general formula (nBu4N)2[Zn(X-phenyloxamide)2] (3) (a, X = 3-NO2; b, X = 4-NO2; c, X = 2,6 CH3; d, X = 3,4-CH3; e, X = 2-Br; f, X = 4-Br; g, X = 2-F;

  摘要在四当量[nBu4N] OH存在下，用一当量的[Zn（OAc）2（H2O）2]（2）处理两当量的N，N'-双（X-苯基）草酰胺（1）生成相应的通式为（nBu4N）2 [Zn（X-X-苯甲酰胺）2]（3）的双（N，N'-取代草酸酯）锌（II）配合物（3）（a，X = 3-NO2; b，X ＝ 4-NO 2； c，X ＝ 2，6-CH 3； d，X ＝ 3，4-CH 3； e，X ＝ 2-Br； f，X ＝ 4-Br； g，X ＝ 2-F； h， X ＝ 4-F； i，X ＝ 2-Cl； j，X ＝ H）。配合物3a–j已通过元素分析，NMR（1H，13C 1H}）和IR光谱进行了表征。另外，已经通过单晶X射线晶体学表征了3a和3f。后面的配合物中的锌（II）离子与来自每个金属中心的两个双齿N，N'-二取代的草酸酯配体的两个乙二酰胺-氮原子四配位。此外，计算得出的3f静电势通过Br…Br
• Structural Diversity in Cyclometalated Diiridium(III) Complexes with Bridging <i>syn</i> and <i>anti</i> μ₂‐Oxamidato and μ₂‐Dithioxamidato Ligands
  作者：Ahmed M'hamedi、Andrei S. Batsanov、Mark A. Fox、Juan A. Aguilar、Martin R. Bryce

  DOI：10.1002/ejic.202300423

  日期：2023.12

  X-ray crystallography, NMR spectroscopy and computations reveal a remarkable diversity of structures in a series of diiridium complexes bridged by μ2-oxamidato and μ2-dithioxamidato ligands.

  X射线晶体学、核磁共振波谱和计算揭示了一系列由μ 2 -草酰胺基和μ 2 -二硫代草酰胺基配体桥接的二铱配合物中结构的显着多样性。
• Heterocycles from heterocycles. 1,3-Diaryl-4,5-imidazolidinediones from 1,3,5-triarylhexahydro-1,3,5-triazines and oxalyl chloride
  作者：Giancarlo Verardo、Angelo G. Giumanini、Fausto Gorassini、Marilena Tolazzi、Paolo Strazzolini

  DOI：10.1016/s0040-4020(01)81552-0

  日期：1993.1

  1,3-Diaryl-4,5-imidazolidinediones ( 6 ) are easily synthesized from 1,3,5-triarylhexahydro-1,3,5-triazines ( 1 ) and oxalyl chloride ( 5 ) in a reaction not likely to involve the zwitterionic intermediate ( 3 ) of the N-methylenearylamine dimer, but viewing the sequential pick up of two units of the monomer ( 2 ) by oxalyl chloride ( 5 ). The essential role of ethyl alcohol added to the reaction mixture is recognized. Reaction conditions have been optimized and some ten imidazolidinediones ( 6 ) were prepared in good to excellent yields. Geometric parameters of 6 were obtained by X-ray diffraction analysis: all the nuclei are found almost in one plane except for a small twist of the phenyl rings about the C-N bond.
• Maringgele, Walter; Sheldrick, George M.; Meller, Anton, Chemische Berichte, 1984, vol. 117, # 6, p. 2112 - 2131
  作者：Maringgele, Walter、Sheldrick, George M.、Meller, Anton、Noltemeyer, Mathias

  DOI：——

  日期：——