N2,N2,4-三甲基-1,2-苯二胺 | 29124-58-1

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 中文名称: N2,N2,4-三甲基-1,2-苯二胺
• 英文名称: 2-Dimethylamino-4-methylanilin
• 英文别名: 4,N²,N²-trimethyl-o-phenylenediamine；4,N²,N²-Trimethyl-o-phenylendiamin；N1,N1,5-Trimethylbenzene-1,2-diamine；2-N,2-N,4-trimethylbenzene-1,2-diamine
• CAS: 29124-58-1
• 化学式: C₉H₁₄N₂
• 分子量: 150.224
• InChiKey: YSDTUUNTLHKWPX-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.4
• 重原子数：
  11
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  29.3
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  四氧嘧啶 、 N2,N2,4-三甲基-1,2-苯二胺 在 盐酸 作用下， 生成 7'-(5-hydroxy-2,4,6-trioxo-hexahydro-pyrimidin-5-yl)-4',6'-dimethyl-3',4'-dihydro-1'H-spiro[pyrimidine-5,2'-quinoxaline]-2,4,6-trione
  参考文献：
  名称：

  Rudy; Cramer, Chemische Berichte, 1939, vol. 72, p. 227,241

  摘要：

  DOI：
• 作为产物：
  描述：

  3,4-二硝基甲苯 在 盐酸 、 tin 、 乙醇 作用下， 生成 N2,N2,4-三甲基-1,2-苯二胺
  参考文献：
  名称：

  Mangini; Colonna, Gazzetta Chimica Italiana, 1938, vol. 68, p. 543,551

  摘要：

  DOI：

文献信息

• Copper-Mediated <i>ortho</i>-C–H Amination Using DMF as the Amine Source
  作者：Tai-Jin Cheng、Jun-Jie Chen、Peng Wu、Hui Xu、Hui-Xiong Dai

  DOI：10.1021/acs.orglett.1c03223

  日期：2021.11.5

  We report herein a copper-mediated ortho-C–H amination of anilines using oxalamide as the directing group and DMF as the amination reagent. This protocol tolerates various functional groups and shows good heterocyclic compatibility. Late-stage dimethylamination of drugs demonstrated the synthetic practicality of the protocol. Mechanistic experiments indicate that a radical pathway may be involved in

  我们在此报道了铜介导的苯胺邻位-C-H 胺化，使用草酰胺作为导向基团，DMF 作为胺化试剂。该协议容忍各种官能团并显示出良好的杂环​​相容性。药物的后期二甲胺化证明了该方案的合成实用性。机械实验表明自由基途径可能参与反应。
• Polyphosphazene derivatives containing carbonyl groups and variously alkylated tertiary amino groups
  申请人：CONSIGLIO NAZIONALE DELLE RICERCHE

  公开号：EP0410287A2

  公开（公告）日：1991-01-30

  Polyphosphazene derivatives containing carbonyl groups and variously alkylated tertiary aminic groups, suited to undergo rapid and efficient photo-crosslinking processes and having general formula: wherein: X represents substituents linked to the polyphosphazene chain by means of hydroxylic or aminic functions and containing carbonyl groups; X′ represents additional substituents linked to the polyphosphazene chain by means of hydroxylic or aminic functions and containing one or more variously alkylated tertiary aminic groups; (w+y+z) is an integer ranging from 20 to 15,000; w and z are integers having a value higher than or equal to zero and at any rate lower than 15,000; y is an integer having a value of from 20 to 15,000;

  含有羰基和各种烷基化叔胺基团的聚磷氮衍生物，适合进行快速高效的光交联过程，其通式为 其中 X 代表通过羟基或氨基功能连接到聚磷链且含有羰基的取代基； X′ 代表通过羟基或氨基官能团与聚磷链键连并含有一个或多个不同烷基化叔胺基的附加取代基； (w+y+z) 是 20 至 15,000 之间的整数； w 和 z 是数值大于或等于零且无论如何小于 15,000 的整数； y 是数值在 20 至 15000 之间的整数；
• Photo-curable resin composition
  申请人：MITSUI PETROCHEMICAL INDUSTRIES, LTD.

  公开号：EP0499435A2

  公开（公告）日：1992-08-19

  A photo-curable resin composition containing a polycarbonate having a number average molecular weight of between 200 and 10,000 and containing at least two (meth)acrylate groups in the molecule, or a diglycidyl phthalate (meth)acrylate, an organic polymer fine powder having an average particle diameter of between 1 µm and 50 µm and a photo-radical polymerization initiator; and a coating liquid to be applied to a resin pattern. This resin composition is useful for preparing a clasp pattern exhibiting a theoretical form for retention, durability, etc., i.e., a cast clasp basic pattern, for producing, by a lost wax method, a cast clasp which is a metal component for holding a partial denture, retaining it and supporting it.

  一种光固化树脂组合物，含有一种聚碳酸酯，其平均分子量在 200 至 10,000 之间，分子中至少含有两个（甲基）丙烯酸酯基团，或邻苯二甲酸二缩水甘油酯（甲基）丙烯酸酯；一种有机聚合物细粉，其平均颗粒直径在 1 微米至 50 微米之间；一种光辐射聚合引发剂；以及一种涂覆在树脂图案上的涂覆液。这种树脂组合物可用于制备一种具有保持力、耐久性等理论形态的扣型，即铸扣基本型，用于通过失蜡法生产铸扣，铸扣是一种用于固定局部义齿、保持义齿和支撑义齿的金属部件。
• DENTAL FILLING REPAIRING MATERIAL
  申请人：Tokuyama Dental Corporation

  公开号：EP2902007A1

  公开（公告）日：2015-08-05

  A dental restorative material including a photocurable composition that contains a polymerizable monomer component (A), an inorganic filler component (B) having an average particle size of not smaller than 0.07 µm, and a photo polymerization initiator (C), the inorganic filler component (B) being contained in an amount of 100 to 1500 parts by mass per 100 parts by mass of the polymerizable monomer component (A), and the polymerizable monomer component (A) and the inorganic filler component (B) being so selected as to satisfy a condition (X1) represented by the following formulas (1a) and (1b): nF-0.005

  一种牙科修复材料，包括一种光固化组合物，其中含有可聚合单体成分（A）、平均粒径不小于 0.07 微米的无机填料成分（B）和光聚合引发剂（C）、 无机填料成分（B）的含量为每 100 重量份可聚合单体成分（A）100 至 1500 重量份，以及 可聚合单体组分（A）和无机填料组分（B）的选择应满足以下公式（1a）和 （1b）所代表的条件（X1）： nF-0.005
• PHOTOCURABLE COMPOSITION AND CURED PRODUCT
  申请人：Shin-Etsu Chemical Co., Ltd.

  公开号：EP3093303A1

  公开（公告）日：2016-11-16

  A photocurable composition comprising (a) a cyano-containing silsesquioxane, (b) a cyano-containing ethylenically unsaturated monofunctional monomer, (c) an ethylenically unsaturated polyfunctional monomer, and (d) a photo-polymerization initiator has a long shelf life under light-shielded conditions. A cured product obtained by curing the photocurable composition is a polymeric material which is transparent and lightweight and has a high dielectric constant.

  由以下物质组成的光固化组合物在遮光条件下具有较长的保质期：(a) 含氰基硅倍半氧 化物；(b) 含氰基乙烯基不饱和单官能团单体；(c) 乙烯基不饱和多官能团单体；(d) 光聚合引发剂。通过固化光固化组合物得到的固化产品是一种透明、轻质、介电常数高的聚合材料。