Octahydro-2H-pyrido[4,3-b]morpholin-3-one hydrochloride

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 恶嗪烷类
• 英文名称: Octahydro-2H-pyrido[4,3-b]morpholin-3-one hydrochloride
• 英文别名: 4a,5,6,7,8,8a-hexahydro-4H-pyrido[4,3-b][1,4]oxazin-3-one;hydrochloride
• 化学式: C7H13ClN2O2
• mdl: MFCD28145252
• 分子量: 192.64
• InChiKey: IGUXMTPEZPXESR-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -1.51
• 重原子数：
  12
• 可旋转键数：
  0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.857
• 拓扑面积：
  50.4
• 氢给体数：
  3
• 氢受体数：
  3

文献信息

• HETEROCYCLIC COMPOUNDS
  申请人：Hoffmann-La Roche Inc.

  公开号：US20210094972A1

  公开（公告）日：2021-04-01

  The invention provides new heterocyclic compounds having the general formulae (Ia) and (Ib) wherein A, B, and L are as described herein, compositions including the compounds, processes of manufacturing the compounds and methods of using the compounds.

  这项发明提供了具有一般式(Ia)和(Ib)的新杂环化合物，其中A、B和L如本文所述，包括这些化合物的组合物，制造这些化合物的过程以及使用这些化合物的方法。
• HETEROCYCLIC COMPOUNDS AS MONOACYLGLYCEROL LIPASE INHIBITORS
  申请人：Hoffmann-La Roche Inc.

  公开号：US20200308190A1

  公开（公告）日：2020-10-01

  The invention provides new heterocyclic compounds having the general formula wherein A, L, X, m, n, R 1 and R 2 are as described herein, compositions including the compounds, processes of manufacturing the compounds and methods of using the compounds.
• [EN] HETEROCYCLIC COMPOUNDS<br/>[FR] COMPOSÉS HÉTÉROCYCLIQUES
  申请人：HOFFMANN LA ROCHE

  公开号：WO2021058444A1

  公开（公告）日：2021-04-01

  The invention provides new heterocyclic compounds having the general formulae (Ia) and (Ib) (Formula Ia, Ib) wherein A, B, and L are as described herein, compositions including the compounds, processes of manufacturing the compounds and methods of using the compounds.