2-Ethyl-4-morpholinoaniline

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 恶嗪烷类
• 英文名称: 2-Ethyl-4-morpholinoaniline
• 英文别名: 2-ethyl-4-morpholin-4-ylaniline
• 化学式: C₁₂H₁₈N₂O
• 分子量: 206.288
• InChiKey: UECXTLMGNRBLJC-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.8
• 重原子数：
  15
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  38.5
• 氢给体数：
  1
• 氢受体数：
  3

文献信息

• PHENYLAMINOPYRIMIDINE AMIDE AUTOPHAGY INHIBITORS AND METHODS OF USE THEREOF
  申请人：Deciphera Pharmaceuticals, LLC

  公开号：US20200354352A1

  公开（公告）日：2020-11-12

  Described herein are compounds that are inhibitors of autophagy and their use in the treatment of disorders such as cancers.

  本文描述了一些抑制自噬作用的化合物，以及它们在治疗癌症等疾病中的应用。
• Phenylaminopyrimidine amide autophagy inhibitors and methods of use thereof
  申请人：Deciphera Pharmaceuticals, LLC

  公开号：US11530206B2

  公开（公告）日：2022-12-20

  Described herein are compounds that are inhibitors of autophagy and their use in the treatment of disorders such as cancers.

  本文描述的化合物是自噬抑制剂，可用于治疗癌症等疾病。
• AMINOPYRIMIDINE AMIDE AUTOPHAGY INHIBITORS AND METHODS OF USE THEREOF
  申请人：Deciphera Pharmaceuticals, LLC

  公开号：US20210128556A1

  公开（公告）日：2021-05-06

  Described herein are compounds that are inhibitors of autophagy and their use in the treatment of disorders such as cancers.
• US9428508B2
  申请人：——

  公开号：US9428508B2

  公开（公告）日：2016-08-30