Thonzonium | 25466-36-8

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚醚
• 英文名称: Thonzonium
• 英文别名: hexadecyl-[2-[(4-methoxyphenyl)methyl-pyrimidin-2-ylamino]ethyl]-dimethylazanium
• CAS: 25466-36-8
• 化学式: C32H55N4O+
• 分子量: 511.8
• InChiKey: IOYZYMQFUSNATM-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  9.9
• 重原子数：
  37
• 可旋转键数：
  22
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.69
• 拓扑面积：
  38.2
• 氢给体数：
  0
• 氢受体数：
  4

文献信息

• SSAT mRNA TRANSLATION REPRESSION AND ACTIVATION
  申请人：Merali Salim

  公开号：US20140234827A1

  公开（公告）日：2014-08-21

  The invention provides an isolated nucleic acid having a sequence encoding a spermidine/spermine acetyltransferase (“SSAT”), wherein translation of an mRNA comprising the encoded SSAT has increased basal translation and increased stimulated translation, compared to a wild-type mRNA encoding SSAT. Methods of use for the nucleic acid are also provided. Methods and compositions are also provided for reducing ischemia-reperfusion injury in organs or tissue for transplantation.
• MICROWELL PLATE FOR HIGH-THROUGHPUT DETECTION AND APPLICATION THEREOF
  申请人：SHANGHAI JIAOTONG UNIVERSITY

  公开号：US20160348148A1

  公开（公告）日：2016-12-01

  A microwell plate for high-throughput detection is provided. The microwell plate includes a plurality of microwell groups, the microwell group includes at least a first microwell and a second microwell, and the microwell group further includes a gas diffusion passage for communicating the first microwell and the second microwell. The application of the microwell plate to high-throughput detection of gas produced through biochemical reaction is also provided. The described methodology is applicable to high-throughput detection and can prevent biological and/or chemical reaction and target substance detection from being interfered with each other, and particularly can attain high-throughput screening of enzyme activity regulators.
• US9585380B2
  申请人：——

  公开号：US9585380B2

  公开（公告）日：2017-03-07
• [EN] ENTPD5 INHIBITORS<br/>[FR] INHIBITEURS DE ENTPD5
  申请人：UNIV TEXAS

  公开号：WO2012065139A2

  公开（公告）日：2012-05-18

  The invention provides methods and pharmaceutical compositions for treating cancer or promoting apoptosis of cancer cells, or reducing the resistance of cancer cells to chemotherapy or apoptosis-promoting therapies by contacting the cancer cells with an ENTPD5-specific inhibitor.
• [EN] ANTIMICROBIAL POLYMER INCORPORATING A QUATERNARY AMMONIUM GROUP<br/>[FR] POLYMÈRE ANTIMICROBIEN COMPORTANT UN GROUPE AMMONIUM QUATERNAIRE
  申请人：CHEMGREEN INNOVATION INC

  公开号：WO2014201544A1

  公开（公告）日：2014-12-24

  The present disclosure relates to antimicrobial polymers which impart prolonged antimicrobial activity to a surface or in a solution, the polymers comprising as repeating monomers a polymerizable cyclic moiety forming part of the polymer backbone and an anti-microbial moiety such as a quaternary ammonium moiety in the side chain. The polymer may further comprise polymerizable units of at least one unsaturated monomer having an ethylenically unsaturated double or triple bond.