N,N-diethyl-2-[2-(2-methyl-5-phenylpyrrol-1-yl)phenoxy]ethanamine;hydron;chloride

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡咯
• 英文名称: N,N-diethyl-2-[2-(2-methyl-5-phenylpyrrol-1-yl)phenoxy]ethanamine;hydron;chloride
• 化学式: C23H29ClN2O
• 分子量: 384.9
• InChiKey: JTOGCNWNXIHUHX-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.6
• 重原子数：
  27
• 可旋转键数：
  8
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.3
• 拓扑面积：
  17.4
• 氢给体数：
  1
• 氢受体数：
  2

文献信息

• INLINE APPLICATION OF COATINGS
  申请人：Cook Medical Technologies LLC

  公开号：EP1993741B1

  公开（公告）日：2014-03-19
• ZEIN COATED MEDICAL DEVICE
  申请人：Med Institute, Inc.

  公开号：EP1981560B1

  公开（公告）日：2010-09-08
• Intraluminal device with a hollow structure
  申请人：Grewe D. David

  公开号：US20070043423A1

  公开（公告）日：2007-02-22

  Intraluminal devices are provided with an inner cavity. The inner cavity may be loaded with a bioactive substance. Fenestrations extend between an outer surface and the inner cavity. Thus, the bioactive substance may be released from the intraluminal device through the fenestrations.
• Implantable medical device coatings with biodegradable elastomer and releasable therapeutic agent
  申请人：Ruane H. Patrick

  公开号：US20070196423A1

  公开（公告）日：2007-08-23

  A coated medical device, such as a stent, that elutes a therapeutic agent in a controlled manner is provided. The medical device may be coated with a layer of therapeutic agent and a layer of bioabsorbable elastomer over the layer of therapeutic agent. Methods of manufacturing a coated medical device and of coating a medical device are also provided.
• Zein coated medical device
  申请人：Ruane H. Patrick

  公开号：US20070207183A1

  公开（公告）日：2007-09-06

  The invention relates to medical devices coated with zein. The medical device may include further a therapeutic agent in contact with zein. Zein allows the therapeutic agent to be retained on the device during delivery and also controls the elution rate of the therapeutic agent following implantation. The invention further relates to methods of delivering a therapeutic agent on said medical devices as well as their use especially in the form of stents for prevention of restenosis.