(1R,2S)-1-[[3-(1-adamantyl)-5-methyl-2-oxidophenyl]methylideneamino]-2,3-dihydro-1H-inden-2-olate;antimony(5+);chromium(3+);hexafluoride

• 分子结构分类: 有机化合物 - 苯类化合物 - 茚满类
• 英文名称: (1R,2S)-1-[[3-(1-adamantyl)-5-methyl-2-oxidophenyl]methylideneamino]-2,3-dihydro-1H-inden-2-olate;antimony(5+);chromium(3+);hexafluoride
• 化学式: C₂₇H₂₉NO₂*Cr*F₆Sb
• 分子量: 687.269
• InChiKey: XOFAKTYSHXLNQZ-XGFKRAQGSA-G

计算性质

• 辛醇/水分配系数(LogP)：
  -14.38
• 重原子数：
  38
• 可旋转键数：
  3
• 环数：
  7.0
• sp3杂化的碳原子比例：
  0.52
• 拓扑面积：
  58.5
• 氢给体数：
  0
• 氢受体数：
  9

反应信息

• 作为产物：
  描述：

  silver hexafluoroantimonate 、 (1R,2S) Jacobsen's chromium catalyst 以 further solvent(s) 为溶剂， 以99%的产率得到(1R,2S)-1-[[3-(1-adamantyl)-5-methyl-2-oxidophenyl]methylideneamino]-2,3-dihydro-1H-inden-2-olate;antimony(5+);chromium(3+);hexafluoride
  参考文献：
  名称：

  Highly Enantio- and Diastereoselective Hetero-Diels-Alder Reactions Catalyzed by New Chiral Tridentate Chromium(III) Catalysts

  摘要：

  Even moderately nucleophilic dienes react with simple aldehydes in the presence of a new Cr(III) catalyst in a hetero-Diels-Alder reaction [Eq. (1)]. Tetrahydropyranyl products with up to three stereogenic centers are generated in near-perfect diastereoselectivities and with greater than 90 % ee (99 % ee for the example shown). TBAF=tetrabutylammonium fluoride; TBS=tert-butyldimethylsilyl; TES=triethylsilyl.

  DOI：

  10.1002/(sici)1521-3773(19990816)38:16<2398::aid-anie2398>3.0.co;2-e

文献信息

• AN EFFICIENT, HIGHLY DIASTEREO- AND ENANTIOSELECTIVE HETERO-DIELS-ALDER CATALYST. PREPARATION OF (2S,6R)-6-(tert-BUTYLDIMETHYL-SILYLOXYMETHYL)-2-METHOXY-2,5-DIHYDROPYRAN
  作者：Chavez, David E.、Jacobsen, Eric N.、Grabowski, E. J. J.、Kubryk, Michele

  DOI：10.15227/orgsyn.082.0034

  日期：——