(2S)-2-(2-hydroxyethylazaniumyl)-3-methylbutanoate

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: (2S)-2-(2-hydroxyethylazaniumyl)-3-methylbutanoate
• 化学式: C7H15NO3
• 分子量: 161.2
• InChiKey: AJNYQRXDVGKEIT-LURJTMIESA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -2.2
• 重原子数：
  11
• 可旋转键数：
  5
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.86
• 拓扑面积：
  69.6
• 氢给体数：
  3
• 氢受体数：
  4

文献信息

• Method for analyzing n-terminal protein adducts
  申请人：Rydberg Per

  公开号：US20070190659A1

  公开（公告）日：2007-08-16

  Method for analyzing adducts in a fluid and/or a solid material suspected of containing the adducts by bringing the material in contact with an isothiocyanate reagent containing a fluorescent. The reagent do not have the isothiocyanate group directly bound to an unsubstituted phenyl or pentafluorophenyl group. A method for manufacturing a standard material for use in the analyzing method, a standard material obtainable by this manufacturing method. Compounds suitable for use as standard material and use of the standard material, and a container for analyzing the adducts are also disclosed. A method for analyzing hazardous substances, a kit including standard material or a compound set out above, an apparatus for performing the analyzing method, and a computer program stored on a data carrier for performing the analyzing method or the manufacturing method are also disclosed.

  一种分析液体和/或固体材料中可能含有的加合物的方法，通过将材料与含有荧光物的异硫氰酸酯试剂接触。该试剂不直接与未取代的苯基或五氟苯基结合的异硫氰酸酯基团。还公开了一种用于分析方法的标准材料制造方法，可获得此制造方法得到的标准材料。还公开了适用于作为标准材料的化合物以及标准材料的使用和用于分析加合物的容器。还公开了一种分析危险物质的方法，包括上述标准材料或化合物集的试剂盒，用于执行分析方法的设备以及存储在数据载体上的用于执行分析方法或制造方法的计算机程序。
• METHOD FOR ANALYZING N-TERMINAL PROTEIN ADDUCTS
  申请人：Adduct Analys AB

  公开号：EP1738177B1

  公开（公告）日：2009-02-11
• METHOD FOR THE MONITORING OF SMOKING CESSATION COMPLIANCE AND RECOVERY, THERAPEUTIC INTERVENTION, AND RISK MANAGEMENT
  申请人：Health Diagnostic Laboratory, Inc.

  公开号：US20130316926A1

  公开（公告）日：2013-11-28

  The invention provides compositions and methods for determining patient compliance with a smoking cessation program, and monitoring the patient for physiological recovery from the deleterious effects of smoking, with particular emphasis on those effects that impact risk of cardiovascular disease and development of cancer. The invention also provides compositions and methods for treating a subject according to the patient compliance with the smoking cessation program.
• US7718437B2
  申请人：——

  公开号：US7718437B2

  公开（公告）日：2010-05-18
• [EN] COMPOUNDS AND COMPOSITIONS FOR USE IN THE PREVENTION AND TREATMENT OF DISORDERS OF FAT METABOLISM AND OBESITY<br/>[FR] COMPOSÉS ET COMPOSITIONS UTILISABLES POUR LA PRÉVENTION ET LE TRAITEMENT DE TROUBLES DU MÉTABOLISME LIPIDIQUE ET DE L'OBÉSITÉ
  申请人：INNODIA INC

  公开号：WO2007107008A1

  公开（公告）日：2007-09-27

  [EN] The invention relates to 4-hydroxyisoleucine, isomers, analogs, lactones, salts, and prodrugs thereof, to processes for their preparation, and to pharmaceutical compositions comprising the same. More particularly, the invention relates to the use of those compounds in the prevention and treatment of disorders of fat metabolism and related syndromes. The invention further relates to the use of those compounds in the prevention and treatment of obesity and related syndromes including, but not limited to, the cosmetic treatment of a mammal in order to effect a cosmetically beneficial loss of body weight, and more particularly loss of body fat.
  [FR] Cette invention concerne le 4-hydroxyisoleucine, des isomères, des analogues, des lactones, des sels et des promédicaments de celui-ci, ainsi que des procédés de préparation et des compositions pharmaceutiques les contenant. Plus particulièrement, cette invention concerne l'utilisation de ces composés pour prévenir et traiter des troubles du métabolisme lipidique ainsi que des syndromes associés. Cette invention concerne également l'utilisation de ces composés pour prévenir et traiter l'obésité ainsi que des syndromes associés, parmi lesquels, entre autres, le traitement esthétique d'un mammifère visant à obtenir une perte de poids esthétiquement avantageuse et plus particulièrement la perte de la graisse corporelle.