3-dimethylsulfonio-N-[4-(3-ethoxy-2-oxoniopropoxy)phenyl]propanimidate | 94055-75-1

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚醚
• 英文名称: 3-dimethylsulfonio-N-[4-(3-ethoxy-2-oxoniopropoxy)phenyl]propanimidate
• CAS: 94055-75-1
• 化学式: C16H26NO4S+
• 分子量: 328.4
• InChiKey: DYZJXZOQQRXDLE-UHFFFAOYSA-O

计算性质

• 辛醇/水分配系数(LogP)：
  1.3
• 重原子数：
  22
• 可旋转键数：
  10
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.56
• 拓扑面积：
  68.8
• 氢给体数：
  2
• 氢受体数：
  4

文献信息

• Anti-allergic pharmaceutical composition for ophthalmic topical administration comprising an inhibitor of IgE production
  申请人：TAIHO PHARMACEUTICAL COMPANY LIMITED

  公开号：EP0624367A1

  公开（公告）日：1994-11-17

  An anti-allergic pharmaceutical composition for ophthalmic topical administration comprises an IgE antibody production inhibitor as an active ingredient, and a process for producing an anti-allergic pharmaceutical composition for ophthalmic topical administration comprises mixing an IgE antibody production inhibitor with a pharmaceutically acceptable carrier, excipient or diluent.

  一种用于眼科局部给药的抗过敏制剂药物组合物包括一种IgE抗体产生抑制剂作为活性成分，制备用于眼科局部给药的抗过敏制剂药物组合物的过程包括将IgE抗体产生抑制剂与药学上可接受的载体、赋形剂或稀释剂混合。
• ANTITHROMBOTIC AGENT
  申请人：Tokai University Educational System

  公开号：EP2505196A1

  公开（公告）日：2012-10-03

  An object of the present invention is to provide an antithrombotic agent that has fewer side effects and that is highly effective. The present invention provides an antithrombotic agent comprising (±)-[2-[4-(3-ethoxy-2-hydroxypropoxy)phenylcarbamoyl]ethyl]dimethylsulfonium p-toluenesulfonate represented by Formula (1) as an active ingredient.

  本发明的目的是提供一种副作用少且高效的抗血栓药。本发明提供了一种抗血栓药，其活性成分包括(±)-[2-[4-(3-乙氧基-2-羟基丙氧基)苯基氨基甲酰基]乙基]二甲基对甲苯磺酸铵，由式（1）代表。
• Tape preparation of WT1 peptide cancer vaccine for transdermal administration
  申请人：NITTO DENKO CORPORATION

  公开号：US10195258B2

  公开（公告）日：2019-02-05

  The present invention provides a cancer vaccine tape preparation for inducing cellular immunity, comprising: a support, an adhesive layer comprising an adhesive disposed on one side of the support, wherein the adhesive layer carries a combination of: (i) a WT1 peptide and/or a modified WT1 peptide; and (ii) a first cellular immunity induction promoter. The tape preparation can provides high efficacy.

  本发明提供了一种用于诱导细胞免疫的癌症疫苗带制剂，包括 一个支架 由粘合剂组成的粘合剂层，粘合剂层设置在支撑物的一侧，其中粘合剂层携带以下物质的组合 (i) WT1 肽和/或修饰的 WT1 肽；以及 (ii) 第一细胞免疫诱导启动子。这种胶带制剂具有很高的功效。
• WT1 peptide cancer vaccine composition for mucosal administration
  申请人：NITTO DENKO CORPORATION

  公开号：US10206985B2

  公开（公告）日：2019-02-19

  The present invention provides a cancer vaccine composition for mucosal administration for inducing cellular immunity, comprising (i) a WT1 peptide and/or a modified WT1 peptide; and (ii) a cellular immunity induction promoter. The composition efficiently induces cellular immunity against a cancer in a subject.

  本发明提供了一种用于粘膜给药以诱导细胞免疫的癌症疫苗组合物，该组合物包含(i)WT1 肽和/或修饰的 WT1 肽；以及(ii)细胞免疫诱导促进剂。该组合物能有效诱导受试者产生抗癌细胞免疫。
• WT1 peptide cancer vaccine composition for transdermal administration
  申请人：NITTO DENKO CORPORATION

  公开号：US10449144B2

  公开（公告）日：2019-10-22

  The present invention provides a cancer vaccine composition for transdermal administration for inducing cellular immunity, comprising (i) a WT1 peptide and/or a modified WT1 peptide; and (ii) a cellular immunity induction promoter. The composition efficiently induces cellular immunity against a cancer in a subject.

  本发明提供了一种用于透皮给药的诱导细胞免疫的癌症疫苗组合物，该组合物包含(i) WT1 肽和/或修饰的 WT1 肽；以及(ii) 细胞免疫诱导促进剂。该组合物能有效诱导受试者产生抗癌细胞免疫。