Magnesiumadipat

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: Magnesiumadipat
• 英文别名: magnesium;hexanedioate
• 化学式: C6H8MgO4
• 分子量: 168.43
• InChiKey: QXNFATVALXHNRJ-UHFFFAOYSA-L

计算性质

• 辛醇/水分配系数(LogP)：
  -2.33
• 重原子数：
  11
• 可旋转键数：
  3
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.67
• 拓扑面积：
  80.3
• 氢给体数：
  0
• 氢受体数：
  4

文献信息

• [EN] PROCESSES FOR PRODUCING MONOAMMONIUM ADIPATE FROM FERMENTATION BROTHS CONTAINING DIAMMONIUM ADIPATE, MONOAMMONIUM ADIPATE AND/OR ADIPIC ACID, AND CONVERSION OF MONOAMMONIUM ADIPATE TO ADIPIC ACID<br/>[FR] PROCÉDÉS DE FABRICATION D'ADIPATE DE MONOAMMONIUM À PARTIR DE BOUILLONS DE FERMENTATION CONTENANT DE L'ADIPATE DE DIAMMONIUM, UN ADIPATE DE MONOAMMONIUM ET/OU DE L'ACIDE ADIPIQUE, ET DE CONVERSION DE L'ADIPATE DE MONOAMMONIUM EN ACIDE ADIPIQUE
  申请人：BIOAMBER SAS

  公开号：WO2011136941A1

  公开（公告）日：2011-11-03

  A process for making MAA from a clarified DAA-containmg fefme.ntation broth includes (a) distilling: the broth to form an overhead thai includes water and ammonia, and a liquid bottoms, that includes MAA, at least some DAA, and at least about 20 wt% water; (fa) cooling "the bottoms to a temperature sufficient to cause the bottoms to separate into a DAA-containing liquid portion in contact with a MAA-contaraing solid portion that is substantially free of DAA; (c) separating the solid portion from the liquid portion: and (d) recovering the solid portion.

  从含有澄清DAA的发酵液中制备MAA的过程包括(a)蒸馏：将发酵液蒸馏成一个包括水和氨的顶部，以及一个包括MAA、至少一些DAA和至少约20wt％水的液体底部；(b)将底部冷却至足以使底部分离成与MAA含量固体部分接触的含有DAA的液体部分，该固体部分基本上不含DAA；(c)分离固体部分和液体部分；和(d)回收固体部分。
• Processes for producing monoammonium adipate from fermentation broths containing diammonium adipate, monoammonium adipate and/or adipic acid, and conversion of monoammonium adipate to adipic acid
  申请人：BioAmber S.A.S.

  公开号：EP2383250A1

  公开（公告）日：2011-11-02

  A process for making MAA from a clarified DAA-containing fermentation broth includes (a) distilling the broth to form an overhead that includes water and ammonia, and a liquid bottoms that includes MAA, at least some DAA, and at least about 20 wt% water; (b) cooling the bottoms to a temperature sufficient to cause the bottoms to separate into a DAA-containing liquid portion in contact with a MAA-containing solid portion that is substantially free of DAA; (c) separating the solid portion from the liquid portion; and (d) recovering the solid portion.

  从含有澄清DAA的发酵液中制备MAA的过程包括：(a)蒸馏发酵液，形成包括水和氨的顶部，以及包括MAA、至少一些DAA和至少约20 wt%水的液体底部；(b)将底部冷却至足以使底部分离为与含有DAA的液体部分接触的MAA含有的几乎不含DAA的固体部分；(c)将固体部分与液体部分分离；和(d)回收固体部分。
• [EN] CARBOXYLATE ACIDIFICATION<br/>[FR] ACIDIFICATION DE CARBOXYLATE
  申请人：PURAC BIOCHEM BV

  公开号：WO2013117687A1

  公开（公告）日：2013-08-15

  The present invention pertains to a method for preparing a carboxylic acid by acidification of a liquid feed comprising a carboxylate salt, which method comprises the steps of - providing a liquid feed comprising magnesium carboxylate; - providing a gas feed comprising gaseous hydrogen chloride; and - acidifying the carboxylate to carboxylic acid by bringing the liquid feed into contact with the gas feed, thereby forming a liquid effluent comprising carboxylic acid and magnesium chloride, wherein the gas feed comprising gaseous hydrogen chloride is derived from a thermal decomposition step wherein an aqueous liquid comprising magnesium chloride is subjected to a temperature of at least 300 °C, thereby decomposing magnesium chloride into magnesium oxide and hydrogen chloride, thus obtaining a solid comprising magnesium oxide and a gas comprising gaseous hydrogen chloride.

  本发明涉及一种通过酸化液体进料制备羧酸的方法，该液体进料包括羧酸盐，该方法包括以下步骤：-提供包含镁羧酸盐的液体进料；-提供包含气态氯化氢的气体进料；并通过将液体进料与气体进料接触来将羧酸盐酸化为羧酸，从而形成包含羧酸和氯化镁的液体流出物，其中包含气态氯化氢的气体进料源自热分解步骤，其中将含有氯化镁的水性液体暴露于至少300°C的温度下，从而将氯化镁分解为氧化镁和氯化氢，从而获得包含氧化镁的固体和包含气态氯化氢的气体。
• Pharmaceutical composition and method for the transdermal delivery of magnesium
  申请人：Brierre T. Barbara

  公开号：US20050196433A1

  公开（公告）日：2005-09-08

  The present invention relates to a method and transdermal pharmaceutical composition for preventing magnesium deficiency or imbalances associated with magnesium deficiency including diabetes, hypertension, high cholesterol, cardiac arrhythmias, acute myocardial infarction, arteriosclerosis, atherosclerosis, preeclampsia, dysautonomia, mitral valve prolapse, asthma, constipation, irritable bowel syndrome, migraines, muscle spasms and cramping, premenstrual syndrome, osteoporosis, kidney stones, chronic fatigue syndrome, and fibromyalgia. The transdermal pharmaceutical composition includes a therapeutically effective amount of a pharmaceutically acceptable salt of magnesium and a pharmaceutically acceptable carrier. A therapeutically effective amount of a pharmaceutically acceptable salt of zinc or a vitamin such as vitamin B 6 or vitamin B 12 , or a combination thereof may also be included in the transdermal pharmaceutical composition. A therapeutically effective amount of progesterone may also be included in the transdermal pharmaceutical composition. The transdermal pharmaceutical composition may be topically administered to prevent magnesium deficiency or imbalances caused by magnesium deficiency.

  本发明涉及一种方法和经皮药物组成物，用于预防与镁缺乏有关的镁缺乏或不平衡，包括糖尿病、高血压、高胆固醇、心律失常、急性心肌梗死、动脉硬化、动脉粥样硬化、先兆子痫、自主神经功能失调、二尖瓣脱垂、哮喘、便秘、肠易激综合征、偏头痛、肌肉痉挛和抽筋、经前综合征、骨质疏松症、肾结石、慢性疲劳综合征和纤维肌痛。经皮药物组成物包括治疗有效量的镁的药用盐和药用载体。经皮药物组成物中还可以包括治疗有效量的锌的药用盐或维生素，如维生素B6或维生素B12，或其组合。经皮药物组成物中还可以包括治疗有效量的孕酮。经皮药物组成物可以局部应用以预防由镁缺乏引起的镁缺乏或不平衡。
• PROCESSES FOR PRODUCING MONOAMMONIUM ADIPATE FROM FERMENTATION BROTHS CONTAINING DIAMMONIUM ADIPATE, MONOAMMONIUM ADIPATE AND/OR ADIPIC ACID, AND CONVERSION OF MONOAMMONIUM ADIPATE TO ADIPIC ACID
  申请人：Fruchey Olan S.

  公开号：US20110266133A1

  公开（公告）日：2011-11-03

  A process for making MAA from a clarified DAA-containing fermentation broth includes (a) distilling the broth to form an overhead that includes water and ammonia, and a liquid bottoms that includes MAA, at least some DAA, and at least about 20 wt % water; (b) cooling the bottoms to a temperature sufficient to cause the bottoms to separate into a DAA-containing liquid portion in contact with a MAA-containing solid portion that is substantially free of DAA; (c) separating the solid portion from the liquid portion; and (d) recovering the solid portion.

  从含有澄清DAA的发酵汁中制备MAA的过程包括(a)蒸馏汁以形成包括水和氨的顶部和包括MAA、至少一些DAA和至少约20重量％水的液体底部; (b)将底部冷却到足以使底部分离成为与MAA含量高且基本上不含DAA的固体部分接触的含有DAA的液体部分; (c)分离固体部分和液体部分; 和(d)回收固体部分。