Ethylbis(3-phenylpropyl)ammonium chloride | 5982-87-6

• 物质功能分类: 化学试剂 - 有机试剂 - 胺盐（铵盐）
• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: Ethylbis(3-phenylpropyl)ammonium chloride
• 英文别名: ethyl-bis(3-phenylpropyl)azanium;chloride
• CAS: 5982-87-6
• 化学式: C20H28ClN
• 分子量: 317.9
• InChiKey: ZKRKHXXSBDSIKQ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.0
• 重原子数：
  22
• 可旋转键数：
  9
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.4
• 拓扑面积：
  3.2
• 氢给体数：
  1
• 氢受体数：
  1

文献信息

• Use of a combination of components with an inhibitory synergistic effect on calcium channels to prevent or treat winkles and fine lines
  申请人：——

  公开号：US20040147443A1

  公开（公告）日：2004-07-29

  Disclosed herein is a composition for topical application to skin, comprising, in a physiologically acceptable medium (i) at least one peptide comprising at least one amino acid sequence derived from the amino acid sequence of the protein SNAP 25, and (ii) at least one calcium-channel inhibitor. Further disclosed is the use of this combination in a composition suitable for topical application to the skin, as an agent for preventing or treating wrinkles and fine lines, such as expression wrinkles, as well as a cosmetic treatment process comprising applying to the skin the composition.

  本文公开了一种用于皮肤局部施用的组合物，该组合物在生理上可接受的介质中包含：(i) 至少一种肽，该肽包含至少一种氨基酸序列，该氨基酸序列来源于蛋白质 SNAP 25 的氨基酸序列；(ii) 至少一种钙通道抑制剂。进一步公开了该组合物在适用于皮肤局部施用的组合物中的用途，作为预防或治疗皱纹和细纹（如表情皱纹）的制剂，以及包括向皮肤施用该组合物的美容治疗过程。
• JP2001114676A
  申请人：——

  公开号：JP2001114676A

  公开（公告）日：2001-04-24
• Use of a combination of components with an inhibitory synergistic effect on calcium channels to prevent or treat wrinkles and fine lines
  申请人：Renault Beatrice

  公开号：US20080050318A1

  公开（公告）日：2008-02-28

  Disclosed herein is a composition for topical application to skin, comprising, in a physiologically acceptable medium (i) at least one peptide comprising at least one amino acid sequence derived from the amino acid sequence of the protein SNAP 25, and (ii) at least one calcium-channel inhibitor. Further disclosed is the use of this combination in a composition suitable for topical application to the skin, as an agent for preventing or treating wrinkles and fine lines, such as expression wrinkles, as well as a cosmetic treatment process comprising applying to the skin the composition.
• US6335368B1
  申请人：——

  公开号：US6335368B1

  公开（公告）日：2002-01-01
• US7071167B2
  申请人：——

  公开号：US7071167B2

  公开（公告）日：2006-07-04