8(S)-Amino-2(R)-methyl-7-oxononanoic acid | 181886-81-7

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: 8(S)-Amino-2(R)-methyl-7-oxononanoic acid
• 英文别名: (2R,8S)-8-amino-2-methyl-7-oxononanoic acid
• CAS: 181886-81-7
• 化学式: C₁₀H₁₉NO₃
• 分子量: 201.26
• InChiKey: YBWPFLPQZXWNNM-SFYZADRCSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -1.6
• 重原子数：
  14
• 可旋转键数：
  7
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.8
• 拓扑面积：
  80.4
• 氢给体数：
  2
• 氢受体数：
  4

文献信息

• USE OF LTB4 INHIBITORS FOR THE TREATMENT OF B-CELL LEUKEMIAS AND LYMPHOMAS
  申请人：Biolipox AB

  公开号：EP1742622A1

  公开（公告）日：2007-01-17
• METHOD AND COMPOSITION FOR TREATING INFLAMMATORY DISORDERS
  申请人：Biolipox AB

  公开号：EP1888033A2

  公开（公告）日：2008-02-20
• Use of Ltb4 Inhibitors for the Treatment of B-Cell Leukemias and Lymphomas
  申请人：Claesson Hans-Erik

  公开号：US20080081835A1

  公开（公告）日：2008-04-03

  The invention relates to the use of an inhibitor of the biosynthesis and/or function of LTB 4 for the manufacture of a medicament for the treatment of B-cell chronic lymphocytic leukemia (B-CLL), B-prolymphocytic leukemia (B-PLL) or B-cell lymphoma. Preferably, the inhibitor of the biosynthesis and/or function of LTB 4 is the inhibitor of 5-LO BWA4C or the inhibitor of FLAP MK-886.
• Method and composition for treating inflammatory disorders
  申请人：Pereswetoff-Morath Lena

  公开号：US20090220583A1

  公开（公告）日：2009-09-03

  There is provided homogeneous pharmaceutical compositions for the treatment of inflammatory disorders comprising an antiinflammatory and/or antihistaminic active ingredient, a polar lipid liposome and a pharmaceutically-acceptable aqueous carrier.
• Method and Composition for Treating Inflammatory Disorders
  申请人：Meda AB

  公开号：US20160166508A1

  公开（公告）日：2016-06-16

  There is provided homogeneous pharmaceutical compositions for the treatment of inflammatory disorders comprising an antiinflammatory and/or antihistaminic active ingredient, a polar lipid liposome and a pharmaceutically-acceptable aqueous carrier.