申请人:Morrison Eric
公开号:US10596117B1
公开(公告)日:2020-03-24
The present invention provides a water continuous dispersion of nanoparticles. The water continuous dispersion includes: one or more aromatic amide anesthetic compounds; one or more polyethoxylated high HLB surfactants; one or more low HLB surfactants; one or more oils, wherein one or more nanoparticles of a dispersed phase include a lipid bilayer, and wherein ratio of oil to surfactant is between about 0.12:1 to about 3.5:1. Methods of preparing various water continuous dispersion of nanoparticles are also provided.
本发明提供了一种纳米颗粒的水连续分散体。该水连续分散液包括:一种或多种芳香族酰胺麻醉化合物;一种或多种聚乙氧基化高 HLB 表面活性剂;一种或多种低 HLB 表面活性剂;一种或多种油,其中分散相的一种或多种纳米粒子包括脂质双分子层,油与表面活性剂的比例在约 0.12:1 至约 3.5:1 之间。还提供了制备各种水连续分散纳米粒子的方法。