α-zearalenone | 675588-20-2

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 大环内酯类和类似物
• 英文名称: α-zearalenone
• 英文别名: (4S,8R)-8,16,18-trihydroxy-4-methyl-3-oxabicyclo[12.4.0]octadeca-1(14),12,15,17-tetraen-2-one
• CAS: 675588-20-2
• 化学式: C₁₈H₂₄O₅
• 分子量: 320.386
• InChiKey: FPQFYIAXQDXNOR-GXTWGEPZSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4
• 重原子数：
  23
• 可旋转键数：
  0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  87
• 氢给体数：
  3
• 氢受体数：
  5

反应信息

• 作为反应物：
  描述：

  戊二酸酐 、 α-zearalenone 在 4-二甲氨基吡啶 作用下， 以 四氢呋喃 为溶剂， 生成
  参考文献：
  名称：

  抗原结构类似物及其在免疫亲和柱柱容量实时监测中的应用、方法和产品

  摘要：

  本发明公开了抗原结构类似物及其在免疫亲和柱柱容量实时监测中的应用、方法和产品。本发明首次提出了采用抗原结构类似物用于免疫亲和柱的实时监测，并基于此开发了一系列抗原结构类似物及免疫亲和柱实时监测产品，解决了包括国标在内的行业方法均无法解决的技术问题，在免疫亲和柱质检领域有着巨大的应用前景。

  公开号：

  CN114957186A

文献信息

• PROCESS FOR MANUFACTURING ZERANOL
  申请人：Bethell John Richard

  公开号：US20120016137A1

  公开（公告）日：2012-01-19

  This invention is directed generally to a process for producing Zeranol that eliminates high pressure and high temperature hydrogenations and provides high selectivity for Zeranol at improved yields.

  本发明通常涉及一种生产Zeranol的过程，该过程消除了高压和高温氢化反应，并在提高产率的同时提供了高选择性的Zeranol。
• BIOMARKER FOR DETECTING ZEARALENONE EFFECT
  申请人：Erber Aktiengesellschaft

  公开号：EP3663413A1

  公开（公告）日：2020-06-10

  The present invention relates to a novel method for detecting zearalenone (ZEN) effect comprising determining the expression level of at least one miRNA in a test sample, as well as to a novel use of at least one miRNA for detecting zearalenone (ZEN) effect in a test sample.

  本发明涉及一种检测玉米赤霉烯酮（ZEN）效应的新方法，该方法包括确定测试样本中至少一种 miRNA 的表达水平，以及至少一种 miRNA 在检测测试样本中玉米赤霉烯酮（ZEN）效应中的新用途。
• Polypeptide for hydrolytic cleavage of zearalenone and/or zearalenone derivatives, isolated polynucleotide thereof as well as a polypeptide containing an additive, use of same as well as a process
  申请人：Erber Aktiengesellschaft

  公开号：US10076125B2

  公开（公告）日：2018-09-18

  The invention relates to a polypeptide for the hydrolytic cleavage of zearalenone and/or at least one zearalenone derivative, said polypeptide being a hydrolase having an amino acid sequence selected from the group consisting of SEQ ID NO: 1-15 or a functional variant thereof, wherein the sequence of the functional variant is at least 40% identical to at least one of the amino acid sequences. The invention also relates to: an additive containing the polypeptide; an isolated polynucleotide that encodes the polypeptide; and a method for the hydrolytic cleavage of zearalenone and/or of at least one zearalenone derivative using the polypeptide.

  本发明涉及一种用于水解裂解玉米赤霉烯酮和/或至少一种玉米赤霉烯酮衍生物的多肽，所述多肽是一种水解酶，其氨基酸序列选自 SEQ ID NO: 1-15 或其功能变体组成的组，其中功能变体的序列与至少一个氨基酸序列至少有 40%相同。本发明还涉及：含有该多肽的添加剂；编码该多肽的分离多核苷酸；以及使用该多肽水解裂解玉米赤霉烯酮和/或至少一种玉米赤霉烯酮衍生物的方法。
• A PROCESS FOR MANUFACTURING ZERANOL
  申请人：Intervet International B.V.

  公开号：EP2417118B1

  公开（公告）日：2016-01-27
• POLYPEPTIDE FOR HYDROLYTIC CLEAVAGE OF ZEARALENONE AND/OR ZEARALENONE DERIVATIVES, ISOLATED POLYNUCLEOTIDE THEREOF AS WELL AS A POLYPEPTIDE CONTAINING AN ADDITIVE, USE OF SAME AS WELL AS A PROCESS
  申请人：Erber Aktiengesellschaft

  公开号：US20160319258A1

  公开（公告）日：2016-11-03

  The invention relates to a polypeptide for the hydrolytic cleavage of zearalenone and/or at least one zearalenone derivative, said polypeptide being a hydrolase having an amino acid sequence selected from the group consisting of SEQ ID NO: 1-15 or a functional variant thereof, wherein the sequence of the functional variant is at least 40% identical to at least one of the amino acid sequences. The invention also relates to: an additive containing the polypeptide; an isolated polynucleotide that encodes the polypeptide; and a method for the hydrolytic cleavage of zearalenone and/or of at least one zearalenone derivative using the polypeptide.