申请人:Roche Diagnostics GmbH
公开号:EP3848708A1
公开(公告)日:2021-07-14
The invention relates to a composition for determining the presence of an esterolytically and/or proteolytically active analyte in an isolated body fluid sample, in particular leukocytes, comprising a diazonium salt, an indoxyl ester capable of producing a colorimetrically detectable reaction product with said diazonium salt, taurine and divalent anions. It further relates to a test device containing said composition, to a method for detecting an esterolytically and/or proteolytically active analyte and to the use of said composition for the detection of an esterolytically and/or proteolytically active analyte in a body fluid sample.
本发明涉及一种用于确定分离体液样品,特别是白细胞中是否存在酯解和/或蛋白水解活性分析物的组合物,该组合物包含重氮盐、能与所述重氮盐产生可通过比色法检测的反应产物的吲哚基酯、牛磺酸和二价阴离子。本发明还涉及一种含有所述组合物的检测装置、一种检测酯解和/或蛋白水解活性分析物的方法,以及使用所述组合物检测体液样品中的酯解和/或蛋白水解活性分析物。