Disclosed are novel compounds having the formula
or a physiologically acceptable salt, amide, ester or prodrug thereof. The compounds can be used to modulate (antagonize, agonize) chemokine receptor function. Also disclosed is a method for treating a patient having an inflammatory disease and/or viral infection comprising administering an effective amount of a compound of Formula I. In particular embodiments, the invention is a method for treating a patient infected with HIV.
本发明涉及一种具有以下公式的新化合物,或其生理上可接受的盐、酰胺、酯或前药。该化合物可用于调节(拮抗、激活)
趋化因子受体功能。本发明还涉及一种治疗患有炎症性疾病和/或病毒感染的患者的方法,包括给患者投予公式I化合物的有效剂量。在特定实施例中,本发明是治疗感染艾滋病毒的患者的方法。