2-Aminoacetic acid;2-[bis(2-hydroxyethyl)amino]ethanol | 72906-07-1

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: 2-Aminoacetic acid;2-[bis(2-hydroxyethyl)amino]ethanol
• CAS: 72906-07-1；72906-08-2；72828-37-6；72828-42-3
• 化学式: C8H20N2O5
• 分子量: 224.26
• InChiKey: XAEBXRXAOJUGOF-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -2.7
• 重原子数：
  15
• 可旋转键数：
  7
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.88
• 拓扑面积：
  127
• 氢给体数：
  5
• 氢受体数：
  7

文献信息

• Hair Loss Prevention by Natural Amino Acid and Peptide Complexes
  申请人：GUPTA SHYAM K

  公开号：US20090253668A1

  公开（公告）日：2009-10-08

  This invention relates to certain skin and hair care agents of formula (I), derived from natural amino acids and peptides. These agents provide multi-functional treatment of enzyme-related skin, hair and scalp problems, for example, hair aging including premature hair loss and hair graying; male pattern baldness; hair loss from dandruff; alopecia; split ends, acne, darkened skin, dark circles around eyes, stretch marks, wrinkles and fine lines, loss of collagen, loss of skin pliability and combinations thereof:

  本发明涉及公式（I）的某些皮肤和头发护理剂，这些护理剂源自天然氨基酸和肽。这些护理剂提供多功能的酶相关皮肤、头发和头皮问题的治疗，例如，头发老化，包括过早脱发和白发；男性型脱发；头皮屑引起的脱发；脱发斑秃；分叉，痤疮，皮肤变黑，眼周黑眼圈，妊娠纹，皱纹和细纹，胶原蛋白流失，皮肤柔韧性流失和它们的组合：
• Skin and Hair Restoration by Natural Amino Acid and Peptide Crown Complexes
  申请人：GUPTA SHYAM K.

  公开号：US20080287536A1

  公开（公告）日：2008-11-20

  This invention relates to certain skin and hair care agents of formula (I), derived from natural amino acids and peptides. These agents provide multi-functional treatment of enzyme-related topical problems, for example, darkened skin including age spots, circles around eyes and stretch marks; skin conditions related to acne including excess facial oil and facial pore size; premature hair aging including hair loss and graying; inflammation including intra-cellular and extra-cellular inflammation; skin aging including wrinkles and fine lines; loss of collagen including thinning skin and loss of skin pliability; malfunction of tyrosinase group of enzymes; malfunction of matrix metalloprotease group of enzymes; and combinations thereof: Wherein, R, R′, and R″=any substituent(s); and M=H, Li, Na, K, Ca, Mg, Zn, Mn, Cu, Fe, Co, Mo, V, Cr, Ammonium, Alkyl ammonium, and Nitrogen Heterocyclic ammonium.

  本发明涉及一种公式（I）的天然氨基酸和肽衍生的某些皮肤和头发护理剂。这些剂提供了多功能的酶相关局部问题治疗，例如黑色皮肤，包括老年斑，眼周圆圈和妊娠纹; 与痤疮相关的皮肤状况，包括过多的面部油脂和面部毛孔大小; 早期头发老化，包括脱发和变白; 炎症，包括细胞内和细胞外炎症; 皮肤老化，包括皱纹和细纹; 胶原蛋白丢失，包括皮肤变薄和失去弹性; 酪氨酸酶类酶的功能障碍; 基质金属蛋白酶酶类的功能障碍; 以及它们的组合：其中，R，R'和R'' = 任何取代基; M = H，Li，Na，K，Ca，Mg，Zn，Mn，Cu，Fe，Co，Mo，V，Cr，铵，烷基铵和氮杂环铵。
• GEL COSMETIC COMPOSITION
  申请人：Kao Corporation

  公开号：EP2057980A1

  公开（公告）日：2009-05-13

  There is provided a cosmetic composition, which stably includes disintegrable particles and is excellent in feeling upon use. A gel cosmetic composition, which has a pH of 4 to 9 and includes the following components (A), (B), (C), (D), and (E): (A) disintegrable particles obtainable binding water-insoluble primary particles by use of a water-soluble binder; (B) 15% to 70% by weight of polyol; (C) a thickening polymer compound having a carboxy group; (D) less than 1% by weight of water-soluble salts; and (E) water.

  本发明提供了一种化妆品组合物，该组合物稳定地包含可分解颗粒，使用时感觉极佳。一种凝胶化妆品组合物，其 pH 值为 4 至 9，包括以下成分（A）、（B）、（C）、 （D）和（E）： (A) 通过使用水溶性粘合剂结合不溶于水的主颗粒而获得的可分解颗粒； (B) 15%至 70%（重量百分比）的多元醇； (C) 具有羧基的增稠聚合物化合物； (D) 少于 1%（按重量计）的水溶性盐；以及 (E) 水。
• SKIN CLEANSING AGENT
  申请人：Kao Corporation

  公开号：EP4066903A1

  公开（公告）日：2022-10-05

  A skin cleansing agent containing the following components (A), (B), and (C): a particle (A) including (A1), (A2), and (A3), (A1) a water-holding oil agent in an amount of from 0.0001 to 13 mass% in the skin cleansing agent, (A2) a moisturizing agent in an amount of from 0.001 to 25 mass% in the skin cleansing agent, and (A3) a polymer; a surfactant (B); and water (C).

  一种洁肤剂，含有以下成分（A）、（B）和（C）：颗粒（A），包括（A1）、（A2）和（A3），（A1）保水油剂，在洁肤剂中的用量为 0.0001 至 13%，（A2）保湿剂，在洁肤剂中的用量为 0.001 至 25%，以及（A3）聚合物；表面活性剂（B）；以及水（C）。
• Novel surfactants and use thereof
  申请人：Sato Yoshinobu

  公开号：US20060062751A1

  公开（公告）日：2006-03-23

  The invention relates to a novel surfactant which is obtained by blending an N—C 8-24 acylamino acid and an alkali salt of an amino acid, and also relates to a detergent composition comprising this surfactant as a cleansing component and an emulsion composition comprising this surfactant as an emulsifying component. In the alkali salt of an amino acid, a suitable amino acid is an acidic or neutral α-amino acid, and a suitable alkali is sodium, potassium, triethanolamine, or N-methyltaurine sodium. In the N—C 8-24 acylamino acid, a suitable amino acid is acidic or neutral, and a suitable C 8-24 acyl is a C 12-18 acyl. This surfactant can provide a detergent composition which ensures good lathering ability and foam quality and which does not cause stiff hair or taut skin after use. The surfactant can also provide an emulsion composition which ensures a good emulsion state.

  本发明涉及一种新型表面活性剂，它是通过将一种 N-C 8-24 酰氨基酸和一种氨基酸的碱式盐混合而得到的新型表面活性剂，还涉及一种由该表面活性剂作为清洁组分的洗涤剂组合物和一种由该表面活性剂作为乳化组分的乳液组合物。在氨基酸的碱盐中，合适的氨基酸是酸性或中性 α-氨基酸，合适的碱是钠、钾、三乙醇胺或 N-甲基牛磺酸钠。在 N-C 8-24 酰氨基中，合适的氨基酸是酸性或中性的，而合适的 C 8-24 酰基是 C 12-18 酰基。这种表面活性剂可以提供一种洗涤剂组合物，确保良好的起泡能力和泡沫质量，使用后不会造成头发僵硬或皮肤紧绷。这种表面活性剂还能提供一种乳液组合物，确保良好的乳液状态。