Cephapirin Benzathine | 97468-37-6

• 物质功能分类: 分析化学 - 标准品 - 药典标准品和杂质标准品
• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: Cephapirin Benzathine
• 英文别名: (6R,7R)-3-(acetyloxymethyl)-8-oxo-7-[(2-pyridin-4-ylsulfanylacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid;N,N'-dibenzylethane-1,2-diamine
• CAS: 97468-37-6
• 化学式: C50H54N8O12S4
• 分子量: 1087.3
• InChiKey: JAHKOXGROZNHHG-RACYMRPCSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.52
• 重原子数：
  74
• 可旋转键数：
  23
• 环数：
  8.0
• sp3杂化的碳原子比例：
  0.32
• 拓扑面积：
  377
• 氢给体数：
  6
• 氢受体数：
  20

文献信息

• Sigma ligands for use in the prevention and/or treatment of postoperative pain
  申请人：Laboratorios del. Dr. Esteve, S.A.

  公开号：EP2353598A1

  公开（公告）日：2011-08-10

  The invention refers to the use of a sigma ligand, particularly a sigma ligand of formulae (I), (II) or (III) to prevent and/or treat acute and chronic pain developed as a consequence of surgery, especially superficial and/or deep pain secondary to surgical tissue injury, and peripheral neuropathic pain, neuralgia, allodynia, causalgia, hyperalgesia, hyperesthesia, hyperpathia, neuritis or neuropathy secondary to surgical procedure.

  本发明涉及使用sigma配体，特别是公式（I），（II）或（III）的sigma配体，以预防和/或治疗由手术引起的急性和慢性疼痛，特别是手术组织损伤引起的表浅和/或深层疼痛，以及周围神经病理性疼痛，神经痛，触痛，烧伤性痛，痛觉过敏，疼痛过敏，神经炎或手术过程引起的神经病变。
• Bacteria Culture Medium and Applications Thereof
  申请人：SHANGHAI PROMOTON BIOTECHNOLOGY CO., LTD.

  公开号：US20160097030A1

  公开（公告）日：2016-04-07

  The present invention has publicized a bacteria culture medium. In common bacteria culture medium, one kind or several kinds of β-lactam antibiotics and/or the salts thereof were premixed. The β-lactam antibiotics and/or the salts thereof premixed in the bacteria culture medium is slightly soluble in water at 25° C. and the solubility is less than 10 mg/ml. The concentrations of the β-lactam antibiotics premixed in the culture medium are greater than the solubility of the used β-lactam antibiotics at 25° C., but are less than 100 mg/ml. The bacteria culture medium can be used to selectively culture bacteria with β-lactam antibiotic resistance and can be stored for a long time.

  本发明公开了一种细菌培养基。在常见的细菌培养基中，一种或几种β-内酰胺类抗生素及/或其盐被预混。在细菌培养基中预混的β-内酰胺类抗生素及/或其盐在25℃下略微溶于水，溶解度小于10 mg/ml。预混在培养基中的β-内酰胺类抗生素的浓度大于25℃下所用β-内酰胺类抗生素的溶解度，但小于100 mg/ml。该细菌培养基可用于选择性培养具有β-内酰胺类抗生素耐药性的细菌，并可长时间储存。
• Use of compounds binding to the sigma receptor for the treatment of diabetes-associated pain
  申请人：LABORATORIOS DEL DR. ESTEVE, S.A.

  公开号：EP1787679A1

  公开（公告）日：2007-05-23

  The present invention refers to the use of compounds active on the sigma receptor for the production of a medicament for the treatment of diabetes-associated pain.

  本发明是指利用对 sigma 受体具有活性的化合物来生产治疗糖尿病相关疼痛的药物。
• Use of compounds binding to the sigma receptor for the treatment of metabolic syndrome
  申请人：LABORATORIOS DEL DR. ESTEVE, S.A.

  公开号：EP1829534A1

  公开（公告）日：2007-09-05

  The present invention refers to the use of compounds binding to the sigma receptor for the treatment of metabolic syndrome.

  本发明是指使用与西格玛受体结合的化合物来治疗代谢综合征。
• Use of compounds binding to the sigma receptor ligands for the treatment of neuropathic pain developing as a consequence of chemotherapy
  申请人：Laboratorios Del. Dr. Esteve, S.A.

  公开号：EP2090311A1

  公开（公告）日：2009-08-19

  The present invention refers to the use of compounds binding to the sigma receptor for the treatment or prevention of neuropathic pain resulting from chemotherapy.

  本发明是指使用与西格玛受体结合的化合物来治疗或预防化疗引起的神经性疼痛。