Hexanoic acid, ester with 1,2,3-propanetriol | 11139-91-6

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: Hexanoic acid, ester with 1,2,3-propanetriol
• 英文别名: hexanoic acid;propane-1,2,3-triol
• CAS: 11139-91-6；26402-23-3
• 化学式: C9H20O5
• 分子量: 208.25
• InChiKey: YEAZPMHWNDZTLC-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.02
• 重原子数：
  14
• 可旋转键数：
  6
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.89
• 拓扑面积：
  98
• 氢给体数：
  4
• 氢受体数：
  5

文献信息

• Corticosteroid topical preparation
  申请人：SHIONOGI & CO., LTD.

  公开号：EP0097374A2

  公开（公告）日：1984-01-04

  A corticosteroid topical preparation which comprises a monoglyceride of a C6-C10 medium-chain fatty acid together with the active ingredient.

  一种皮质类固醇外用制剂，由 C6-C10 中链脂肪酸单甘油酯和活性成分组成。
• RESIN COMPOSITION AND MOLDING PRODUCED THEREFROM
  申请人：SHOWA DENKO KABUSHIKI KAISHA

  公开号：EP0565734A1

  公开（公告）日：1993-10-20

  A resin composition comprising a specified ethylenic copolymer, a polyhydric alcohol and a reaction promoter, and a thermally reversibly cross-linking molding produced therefrom. Because both the composition and the molding have a high cross-linkage dissociating velocity when heated and a high cross-linkage forming velocity when cooled, they can be utilized in various applications including melt molding as substantially practicable, thermally reversibly cross-linking composition and molding.

  一种由特定乙烯共聚物、多元醇和反应促进剂组成的树脂组合物，以及由其制成的热可逆交联模塑物。由于该组合物和模塑物在加热时具有较高的交联解离速度，在冷却时具有较高的交联形成速度，因此可用于各种应用，包括熔融模塑、热可逆交联组合物和模塑。
• PHARMACEUTICAL COMPOSITION FOR ORAL ADMINISTRATION
  申请人：DAIICHI PHARMACEUTICAL CO., LTD.

  公开号：EP0953359A1

  公开（公告）日：1999-11-03

  The present invention is directed to a pharmaceutical composition for oral administration, comprising a basic drug, a lipophilic substance, and/or a cyclodextrin. The composition exhibits improved peroral absorption of a basic drug which is difficult to be absorbed by oral administration.

  本发明涉及一种口服药物组合物，其中包括一种碱性药物、一种亲脂性物质和/或一种环糊精。 该组合物改善了难以通过口服吸收的碱性药物的口腔吸收。
• ANTI-NOROVIRUS AGENT, AND COMPOSITION COMPRISING THE SAME
  申请人：Hiroshima University

  公开号：EP2153838A1

  公开（公告）日：2010-02-17

  The present invention aims to provide an anti-norovirus agent that has high norovirus-inactivating activity and is safe for the human body, and an anti-norovirus composition that contains the anti-norovirus agent and is useful for disinfection and infection control against the norovirus. An anti-norovirus agent according to the present invention is characterized by containing, as an active ingredient, an extract from a plant of the genus Diospyros containing tannin (hereinafter referred to as a "persimmon extract"), preferably a persimmon extract produced by heating squeezed juice or an extract from the fruit of a plant of the genus Diospyros or treating the squeezed juice or the extract with an alcohol. An anti-norovirus composition according to the present invention is characterized by containing the anti-norovirus agent and at least one selected from the group consisting of alcohols, surfactants, bactericides, humectants, and cosmetic fats and oils, and preferably further containing an organic acid, such as citric acid, and/or a salt thereof or vitamin C.

  本发明的目的是提供一种具有高诺沃克病毒灭活活性且对人体安全的抗诺沃克病毒制剂，以及一种含有该抗诺沃克病毒制剂且可用于诺沃克病毒消毒和感染控制的抗诺沃克病毒组合物。根据本发明的抗诺沃克病毒剂，其特征在于含有一种含单宁的柿属植物提取物（以下简称 "柿提取物"）作为活性成分，最好是通过加热柿属植物果实的榨汁或提取物或用酒精处理榨汁或提取物而产生的柿提取物。根据本发明的抗诺罗病毒组合物的特点是含有抗诺罗病毒剂和至少一种选自醇、表面活性剂、杀菌剂、保湿剂和化妆品油脂组成的组，最好还含有一种有机酸，如柠檬酸和/或其盐或维生素 C。
• COMPOSITION FOR HYDROPHILIC CURED PRODUCT
  申请人：Mitsui Chemicals, Inc.

  公开号：EP3081578A1

  公开（公告）日：2016-10-19

  Objects of the present invention are to provide a composition which can easily give cured products enriched with hydrophilic groups at the surface, and a composition which can give cured products while ensuring that the surface is enriched with hydrophilic groups which are hardly concentrated at the surface by conventional methods; to provide cured products obtained from such compositions; to provide a composition which is suited for producing cured products having high and long-lasting hydrophilicity and also having high surface smoothness; and to provide a cured product obtained from the composition. A monolayer film is fabricated which includes a crosslinked resin obtained by polymerizing a composition including a compound (I) having at least one hydrophilic group selected from anionic hydrophilic groups, cationic hydrophilic groups and hydroxyl groups, and at least one functional group with a polymerizable carbon-carbon double bond (wherein the number of the functional groups with a polymerizable carbon-carbon double bond is one when the hydrophilic group is a hydroxyl-containing group); a compound (II) having two or more functional groups with a polymerizable carbon-carbon double bond (wherein the compound may have a hydroxyl group but is free from anionic hydrophilic groups and cationic hydrophilic groups); and at least one compound selected from a surfactant (III) having a hydrophilic moiety including an anionic hydrophilic group, a cationic hydrophilic group or two or more hydroxyl groups, and a hydrophobic moiety including an organic residue, and a compound (IV) having a siloxane bond and a molecular weight of 200 to 1,000,000 (wherein the surfactant (III) and the compound (IV) have no polymerizable carbon-carbon double bonds). The monolayer film has a gradient of hydrophilic group concentration (Sa/Da) of not less than 1.1 wherein Sa is the surface concentration of at least one type of hydrophilic groups selected from anionic hydrophilic groups, cationic hydrophilic groups and hydroxyl groups, and Da is the deep concentration of the hydrophilic groups at 1/2 of the thickness of the monolayer film.

  本发明的目的是提供一种组合物，该组合物可以很容易地得到表面富含亲水基团的固化产品，以及一种组合物，该组合物可以在得到固化产品的同时确保表面富含亲水基团，而通过传统方法，亲水基团很难集中在表面上；提供由这种组合物得到的固化产品；提供一种组合物，该组合物适合生产具有高且持久亲水性的固化产品，同时还具有高表面光滑度；以及提供由该组合物得到的固化产品。本发明制备了一种单层膜，该单层膜包括通过聚合一种组合物而获得的交联树脂，该组合物包括一种化合物 (I)，该化合物具有至少一个亲水基团，该亲水基团选自阴离子亲水基团、阳离子亲水基团和羟基，以及至少一个具有可聚合碳碳双键的官能团（其中当亲水基团为含羟基基团时，具有可聚合碳碳双键的官能团的数目为一个）；具有两个或两个以上具有可聚合碳碳双键的官能团的化合物 (II)（其中该化合物可具有羟基，但不含阴离子亲水基团和阳离子亲水基团）；以及至少一种选自表面活性剂（III）的化合物，该表面活性剂具有包括阴离子亲水基团、阳离子亲水基团或两个或多个羟基在内的亲水分子，以及包括有机残留物在内的疏水分子，以及具有硅氧烷键且分子量在 200-1,000,000 之间的化合物（IV）（其中表面活性剂（III）和化合物（IV）不具有可聚合的碳碳双键）。单层膜的亲水基团浓度梯度（Sa/Da）不小于 1.1，其中 Sa 是选自阴离子亲水基团、阳离子亲水基团和羟基的至少一种亲水基团的表面浓度，Da 是亲水基团在单层膜厚度的 1/2 处的深度浓度。