(4-Methyl-piperidin-1-yl)-acetic acid, methyl ester

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: (4-Methyl-piperidin-1-yl)-acetic acid, methyl ester
• 英文别名: methyl 2-(4-methylpiperidin-1-yl)acetate
• 化学式: C₉H₁₇NO₂
• mdl: MFCD06081009
• 分子量: 171.24
• InChiKey: FHGBJZGJGNTNDT-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.5
• 重原子数：
  12
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.888
• 拓扑面积：
  29.5
• 氢给体数：
  0
• 氢受体数：
  3

文献信息

• 7-oxo-pyridopyrimidines (II)
  申请人：——

  公开号：US20020055513A1

  公开（公告）日：2002-05-09

  The present invention provides compounds of the formula: 1 a prodrug or a pharmaceutically acceptable salt thereof, wherein R 1 , R 2 , R 3 and Ar 1 are those defined herein, and methods for preparation and uses thereof.

  本发明提供了以下公式的化合物：1a前体或其药用可接受的盐，其中R1、R2、R3和Ar1是在此定义的，以及其制备方法和用途。
• 1,3,4-OXADIAZOLE AND 1,3,4-THIADIAZOLE BETA-LACTAMASE INHIBITORS
  申请人：Cubist Pharmaceuticals, Inc.

  公开号：US20130296290A1

  公开（公告）日：2013-11-07

  β-Lactamase inhibitor compounds (BLIs) are disclosed, including compounds that have activity against class A, class C or class D β-lactamases. Methods of manufacturing the BLIs, and uses of the compounds in the preparation of pharmaceutical compositions and antibacterial applications are also disclosed.

  本文披露了β-内酰胺酶抑制剂化合物（BLIs），其中包括对A类、C类或D类β-内酰胺酶具有活性的化合物。本文还披露了制造BLIs的方法，以及在制备药物组合物和抗菌应用中使用这些化合物的方法。
• ANTIMICROBIAL COMPOUNDS AND METHODS OF MAKING AND USING THE SAME
  申请人：Melinta Therapeutics, Inc.

  公开号：US20150274752A1

  公开（公告）日：2015-10-01

  The present invention relates generally to the field of antimicrobial compounds and to methods of making and using them. These compounds are useful for treating, preventing, and/or reducing the risk of microbial infections in humans and animals.

  本发明通常涉及抗微生物化合物领域及其制备和使用方法。这些化合物对于治疗、预防和/或降低人类和动物微生物感染的风险具有用处。
• AMIDE DERIVATIVES OF ETHACRYNIC ACID
  申请人：Carson Dennis A.

  公开号：US20110306671A1

  公开（公告）日：2011-12-15

  The invention provides ethacrynic acid derivatives useful to prevent, inhibit or treat a variety of disorders or diseases including cancer and inflammatory disorders.
• 5-CHLORO-2-DIFLUOROMETHOXYPHENYL PYRAZOLOPYRIMIDINE COMPOUNDS,COMPOSITIONS AND METHODS OF USE THEREOF
  申请人：Genentech, Inc.

  公开号：US20170145020A1

  公开（公告）日：2017-05-25

  Compounds of Formula (00A) and methods of use as Janus kinase inhibitors are described herein.