Pentacosanamide | 873393-40-9

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: Pentacosanamide
• CAS: 873393-40-9
• 化学式: C₂₅H₅₁NO
• 分子量: 381.7
• InChiKey: KURAXKCEFNOSHP-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  10.6
• 重原子数：
  27
• 可旋转键数：
  23
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.96
• 拓扑面积：
  43.1
• 氢给体数：
  1
• 氢受体数：
  1

文献信息

• Novel ultrasound contrast agents
  申请人：——

  公开号：US20040170565A1

  公开（公告）日：2004-09-02

  New ultrasound contrast agents that comprise microbubbles encapsulating a gas within a shell made from a blend of bipolar compounds having mixed carbon chain length. The compounds have hydrophobic groups selected from the group consisting of straight-chained alkyls, alkylethers, alkylthiolethers, alkyldisulfides, polyfluoroalkyls, and polyfluoroalkylethers having a carbon chain length greater than or equal to 16 and less than or equal to 32. The polar groups are connected to the hydrophobic groups by means of a linker. The polar head groups are selected from the group consisting of CO 2 -M + , SO 3 − M + , SO 4 − M + , PO 3 − M + , PO 4 − M + 2 , N(R) 4 + , a pyridinium or substituted pyridinium group, and a zwitterionic group; R is selected from the group consisting of —H, —CH 3 , alkyl, cycloalkyl, substituted cycloalkyls containing one or more heteroatoms, and benzyl and can be the same or different; and Z′ is a nonionic and M is a cation.

  新的超声造影剂包括微泡，其内部封装有气体，外壳由混合的双极化合物制成，其碳链长度混合。这些化合物具有疏水基团，所选的疏水基团来自于直链烷基，烷基醚，烷基硫醚，烷基二硫化物，多氟烷基和碳链长度大于或等于16且小于或等于32的多氟烷基醚。极性基团通过连接剂连接到疏水基团上。极性头基团来自于CO2-M+，SO3−M+，SO4−M+，PO3−M+，PO4−M+2，N(R)4+，吡啶或取代吡啶基团和带电离子的基团；R来自于—H，—CH3，烷基，环烷基，含有一个或多个杂原子的取代环烷基和苄基，并且可以相同也可以不同；Z′是非离子性的，M是一个阳离子。
• 1,2-Diphenylpyrrole derivatives, their preparation and their therapeutic uses
  申请人：SANKYO COMPANY LIMITED

  公开号：EP0799823A1

  公开（公告）日：1997-10-08

  Compounds of formula (I) and (II): [in which R is hydrogen, halogen or alkyl; R1 is alkyl, amino or substituted amino; R2 is optionally substituted phenyl; R3 is hydrogen, halogen or optionally substituted alkyl; R4 is hydrogen, optionally substituted alkyl, cycloalkyl, aryl, or aralkyl] have valuable analgesic, anti-inflammatory, anti-pyretic and anti-allergic activities and have the ability to inhibit the production of leukotrienes and to inhibit bone resorption. They are relatively free from the side effects which generally result from the administration of compounds having these kinds of activities.

  式(I)和(II)化合物： [其中 R 是氢、卤素或烷基；R1 是烷基、氨基或取代氨基；R2 是任选取代的苯基；R3 是氢、卤素或任选取代的烷基；R4 是氢、任选取代的烷基、环烷基、芳基或芳烷基]具有重要的镇痛、消炎、解热和抗过敏活性，并能抑制白三烯的生成和抑制骨吸收。它们相对来说没有副作用，而副作用通常是由服用具有此类活性的化合物引起的。
• POLYMER
  申请人：Sumitomo Chemical Company, Ltd.

  公开号：EP3235836A1

  公开（公告）日：2017-10-25

  Provided is a polymer that is capable of affording a heat storage material superior in humidity permeability and shape retention after phase transition and that is superior in molding processability, namely, a polymer including constitutional units (A) derived from ethylene, constitutional units (B) represented by a specified formula, and optionally including constitutional units (C) represented by a specified formula, wherein where the total number of the units (A), the units (B), and the units (C) is 100%, the number of the units (A) accounts for 70% to 99%, the total number of the units (B) and the units (C) accounts for 1% by weight to 30% by weight, and where the total number of the units (B) and the units (C) is 100%, the number of the units (B) accounts for 1% to 100% and the number of the units (C) accounts for 0% to 99%.

  本发明提供了一种聚合物，该聚合物能够提供一种在相变后湿度渗透性和形状保持性方面更优越且在成型加工性方面更优越的蓄热材料，即一种包括由乙烯衍生的组成单元（A）、由指定式表示的组成单元（B）以及可选地包括由指定式表示的组成单元（C）的聚合物、其中，当单元（A）、单元（B）和单元（C）的总数量为 100%时，单元（A）的数量占 70%至 99%，单元（B）和单元（C）的总数量占 1%至 30%（按重量计），而当单元（B）和单元（C）的总数量为 100%时，单元（B）的数量占 1%至 100%，单元（C）的数量占 0%至 99%。
• RESIN PRODUCT AND MEDICINAL COMPONENT DISPENSING DEVICE
  申请人：Sumitomo Chemical Company, Limited

  公开号：EP3385332A1

  公开（公告）日：2018-10-10

  The present invention provides a resin product comprising: an active ingredient; a thermoplastic resin (2) having a melting enthalpy (ΔH) of 30 J/g or more, as observed by differential scanning calorimetry within a temperature range of 10°C or more and less than 60°C; and a thermoplastic resin (3) having a storage elastic modulus E' at 60°C of 5.0 × 105 Pa or more, as determined by dynamic viscoelasticity measurement at a frequency of 10 Hz. The present invention also provides a molded article comprising the resin product and a device for sustained-release of an active ingredient comprising a component consisting of the resin product.

  本发明提供了一种树脂产品，包括：活性成分；热塑性树脂（2），其熔化焓（ΔH）为 30 J/g 或更高，通过差示扫描量热法在 10°C 或更高且低于 60°C 的温度范围内进行观察；以及热塑性树脂（3），其在 60°C 时的存储弹性模量 E' 为 5.0 × 105 Pa 或更高，通过频率为 10 Hz 的动态粘弹性测量进行测定。本发明还提供了一种由该树脂产品组成的模塑制品和一种由该树脂产品组成的活性成分持续释放装置。
• POLYMER, MOLDED BODY, FOAM, RESIN COMPOSITION, AND PRODUCTION METHOD FOR POLYMER
  申请人：Sumitomo Chemical Company Limited

  公开号：EP3473653A1

  公开（公告）日：2019-04-24

  Provided is a polymer having a sharp melting peak and allowing easy adjustment of the melting peak temperature. Specifically provided is a polymer comprising: two or more kinds of constitutional units containing an alkyl group having 14 or more and 30 or less carbon atoms, wherein the proportions of the number of the two or more kinds of constitutional units containing an alkyl group having 14 or more and 30 or less carbon atoms are each 20% or more, with respect to 100% of the total number of all constitutional units containing an alkyl group having 14 or more and 30 or less carbon atoms, and an enthalpy of fusion of the polymer observed within a temperature range of 10°C or higher and lower than 60°C in differential scanning calorimetry is 30 J/g or more.

  本发明提供了一种聚合物，该聚合物具有尖锐的熔峰，且易于调节熔峰温度。具体而言，该聚合物包括两种或两种以上含有碳原子数分别为 14 个或 14 个以上和 30 个或 30 个以下的烷基的结构单元，其中两种或两种以上含有碳原子数分别为 14 个或 14 个以上和 30 个或 30 个以下的烷基的结构单元的数量占所有含有碳原子数分别为 14 个或 14 个以上和 30 个以下的烷基的结构单元总数的比例均为 20%或 20%以上，且在差示扫描量热法中观察到聚合物在高于 10°C 和低于 60°C 的温度范围内的熔融焓为 30 焦耳/克或 30 焦耳/克以上。