N-[2-(Aminocarbonyl)benzoyl]-L-glutamic acid | 270902-50-6

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: N-[2-(Aminocarbonyl)benzoyl]-L-glutamic acid
• 英文别名: (2S)-2-[(2-carbamoylbenzoyl)amino]pentanedioic acid
• CAS: 270902-50-6
• 化学式: C₁₃H₁₄N₂O₆
• 分子量: 294.26
• InChiKey: HXUZSNAZGJETIN-VIFPVBQESA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.4
• 重原子数：
  21
• 可旋转键数：
  7
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.23
• 拓扑面积：
  147
• 氢给体数：
  4
• 氢受体数：
  6

文献信息

• Methods for diagnosing and treating neuroendocrine cancer
  申请人：North William G.

  公开号：US20080145849A1

  公开（公告）日：2008-06-19

  The present invention relates to a method for diagnosing neuroendocrine cancers via detecting the presence of N-methyl D-asparate-associated (NMDA) glutamate receptors type 1 and/or type 2. Methods for preventing and treating neuroendocrine cancers are also disclosed.
• Methods for Diagnosing and Treating Neuroendocrine Cancer
  申请人：North William G.

  公开号：US20110014202A1

  公开（公告）日：2011-01-20

  The present invention relates to a method for diagnosing neuroendocrine cancers via detecting the presence of N-methyl D-asparate-associated (NMDA) glutamate receptors type 1 and/or type 2. Methods for preventing and treating neuroendocrine cancers are also disclosed.
• METHODS FOR DIAGNOSING AND TREATING NEUROENDOCRINE CANCER
  申请人：Trustees of Dartmouth College

  公开号：US20140050730A1

  公开（公告）日：2014-02-20

  The present invention relates to a method for diagnosing neuroendocrine cancers via detecting the presence of N-methyl D-asparate-associated (NMDA) glutamate receptors type 1 and/or type 2. Methods for preventing and treating neuroendocrine cancers are also disclosed.
• METHOD FOR TREATING NEUROENDOCRINE CANCER
  申请人：Trustees of Dartmouth College

  公开号：US20160068599A1

  公开（公告）日：2016-03-10

  Methods for decreasing proliferation and preventing or treating a neuroendocrine cancer using an N-methyl D-aspartate-associated (NMDA) glutamate receptor antagonists or binding agent, such as an antibody, antibody fragment or peptide aptamer specific for a NMDA glutamate receptor, are disclosed.
• US7842468B2
  申请人：——

  公开号：US7842468B2

  公开（公告）日：2010-11-30