5-methyl-2-(4-methylphenoxy)-phenol | 1027075-68-8

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 5-methyl-2-(4-methylphenoxy)-phenol
• 英文别名: o-Hydroxy-di-(p-tolyl)-aether；5-Methyl-2-(4-methylphenoxy)phenol
• CAS: 1027075-68-8
• 化学式: C₁₄H₁₄O₂
• 分子量: 214.264
• InChiKey: KVCHBONVFKPGJZ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.8
• 重原子数：
  16
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.14
• 拓扑面积：
  29.5
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  5-methyl-2-(4-methylphenoxy)-phenol 、 三甲基乙酰氯 在 三乙胺 作用下， 以 四氢呋喃 为溶剂， 反应 2.0h， 以90%的产率得到
  参考文献：
  名称：

  Synthesis and antibacterial activity of littorachalcone and related diphenyl ethers

  摘要：

  Littorachalcone (1) and diacid 10 were synthesized by direct routes. The antibacterial activity of 1, 10 and synthetic precursors were evaluated. Dialdehyde 3a showed potent antibacterial activity. (C) 2008 Published by Elsevier Ltd.

  DOI：

  10.1016/j.bmcl.2008.02.082
• 作为产物：
  描述：

  在 sodium hydroxide 、 双氧水 作用下， 以 四氢呋喃 、 乙醚 、 正己烷 为溶剂， 反应 3.0h， 以1.75 g的产率得到5-methyl-2-(4-methylphenoxy)-phenol
  参考文献：
  名称：

  Synthesis and antibacterial activity of littorachalcone and related diphenyl ethers

  摘要：

  Littorachalcone (1) and diacid 10 were synthesized by direct routes. The antibacterial activity of 1, 10 and synthetic precursors were evaluated. Dialdehyde 3a showed potent antibacterial activity. (C) 2008 Published by Elsevier Ltd.

  DOI：

  10.1016/j.bmcl.2008.02.082

文献信息

• Enhancing the Antimicrobial Activity of Biocides with Polymers
  申请人：BASF SE

  公开号：US20140369953A1

  公开（公告）日：2014-12-18

  Disclosed are compositions comprising a) an antimicrobial agent, which is selected from the group consisting of biocides containing halogen atoms and/or containing phenolic moieties, formic acid, chlorine dioxide, chlorine dioxide generating compounds, dialdehydes; components containing an antimicrobial metal such as antimicrobial silver, and b) a polyamine, especially a polyethylenimine. The polyamine is effective as a booster for the antimicrobial agent.