3-hydroxymethyl-2,2,5,5-tetramethylimidazolidine-4-one | 350810-08-1

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: 3-hydroxymethyl-2,2,5,5-tetramethylimidazolidine-4-one
• 英文别名: MTMIO；3-(Hydroxymethyl)-2,2,5,5-tetramethylimidazolidin-4-one
• CAS: 350810-08-1
• 化学式: C₈H₁₆N₂O₂
• 分子量: 172.227
• InChiKey: MTRSRVMIFQFRBU-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.4
• 重原子数：
  12
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.88
• 拓扑面积：
  52.6
• 氢给体数：
  2
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  3-hydroxymethyl-2,2,5,5-tetramethylimidazolidine-4-one 在 sodium hypochlorite 作用下， 以 水 为溶剂， 生成 1-chloro-3-hydroxymethyl-2,2,5,5-tetramethylimidazolidine-4-one
  参考文献：
  名称：

  ANTIBACTERIAL HYDROPHILIC COMPOUND AND USE THEREOF

  摘要：

  本公开提供一种抗菌亲水化合物。该抗菌亲水化合物可以通过其结构式中的氢抽取基团受光诱导反应，与C—H基团发生作用，从而结合到具有C—H基团的材料表面（例如，化学纤维如涤纶、尼龙等；塑料、橡胶和其他类似材料），从而赋予材料耐久的抗菌活性和亲水性。该抗菌亲水化合物对材料表面具有相对较强的结合力，而不会损害原材料的机械性能。本公开还提供一种由该抗菌亲水化合物改性的材料。

  公开号：

  US20200093124A1

文献信息

• Biocidal polyester and methods
  申请人：Auburn University

  公开号：US20030064645A1

  公开（公告）日：2003-04-03

  Biocidal polyester fabrics, fibers and other materials, and methods of preparation. Heterocyclic N-halamine precursor moieties are covalently linked to the polyester material. The fabrics or fibers obtain antimicrobial activity after washing with a source of oxidative halogen such as a chlorine bleach by conversion of the precursor moieties into N-halamine functionalities. The antimicrobial activity can be repeatedly regenerated by further washing with aqueous oxidative halogen. The biocidal polyester fabrics, fibers, and other materials will be effective in reducing, or eliminating entirely, pathogenic and odor-causing microorganisms.

  杀菌聚酯织物、纤维和其他材料及其制备方法。杂环 N-卤胺前体分子与聚酯材料共价连接。通过将前体分子转化为 N-卤胺官能团，在使用氯漂白剂等氧化卤源洗涤后，织物或纤维可获得抗菌活性。抗菌活性可通过进一步使用氧化卤素水溶液洗涤反复再生。这种杀菌聚酯织物、纤维和其他材料可有效减少或完全消除致病和致臭微生物。
• US4804717A
  申请人：——

  公开号：US4804717A

  公开（公告）日：1989-02-14
• [EN] BIOCIDAL POLYAMIDES AND METHODS<br/>[FR] POLYAMIDES BIOCIDES ET PROCEDES ASSOCIES
  申请人：UNIV AUBURN

  公开号：WO2002006579A2

  公开（公告）日：2002-01-24

  Biocidal polyamide materials such as deodorant and/or biocidal Nylon® polyamide fibers, fabrics and surfaces and biocidal Aramid (such as Kevlar® and Nomex®) fibers, fabrics and surfaces, and methods of preparation. Heterocyclic N-halamine precursor moieties are covalently linked to the polyamide material. The fabrics and/or fibers thereafter obtain antimicrobial activity after washing with a halogenated solution to convert the heterocyclic precursor moieties into heterocyclic N-halamines. The antimicrobial activity against pathogenic microorganism can be repeatedly regenerated by washings with a halogenated solution.
• ANTIBACTERIAL HYDROPHILIC COMPOUND AND USE THEREOF
  申请人：SHENZHEN UNIVERSITY

  公开号：US20200093124A1

  公开（公告）日：2020-03-26

  The present disclosure provides an antibacterial hydrophilic compound. The antibacterial hydrophilic compound may react, induced by light through a hydrogen abstraction group in the structural formula thereof, with a C—H group and thus bind to a surface of a material having the C—H group (for example, chemical fibers such as polyester, chinlon, and the like; plastics, rubbers, and other similar materials), which can impart a durable antibacterial activity and hydrophilicity to the material. The antibacterial hydrophilic compound has a relatively strong binding force to the surface of the material without damaging the mechanical properties of the raw material. The present disclosure also provides a modified material that is modified by the antibacterial hydrophilic compound.

  本公开提供一种抗菌亲水化合物。该抗菌亲水化合物可以通过其结构式中的氢抽取基团受光诱导反应，与C—H基团发生作用，从而结合到具有C—H基团的材料表面（例如，化学纤维如涤纶、尼龙等；塑料、橡胶和其他类似材料），从而赋予材料耐久的抗菌活性和亲水性。该抗菌亲水化合物对材料表面具有相对较强的结合力，而不会损害原材料的机械性能。本公开还提供一种由该抗菌亲水化合物改性的材料。