(3Z,5E)-3,5-bis[(2,3,4-trimethoxyphenyl)methylene]tetrahydrothiopyran-4-one

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚醚
• 英文名称: (3Z,5E)-3,5-bis[(2,3,4-trimethoxyphenyl)methylene]tetrahydrothiopyran-4-one
• 英文别名: (3E,5Z)-3,5-bis[(2,3,4-trimethoxyphenyl)methylidene]thian-4-one
• 化学式: C₂₅H₂₈O₇S
• 分子量: 472.6
• InChiKey: ZMHGZRIEKXTPDW-MJZABRMRSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.1
• 重原子数：
  33
• 可旋转键数：
  8
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.32
• 拓扑面积：
  97.8
• 氢给体数：
  0
• 氢受体数：
  8

文献信息

• [EN] COMPOUNDS FOR TREATING INFLAMMATORY AND HYPERPROLIFERATIVE DISEASES<br/>[FR] COMPOSÉS POUR TRAITER DES MALADIES INFLAMMATOIRES ET HYPERPROLIFÉRATIVES
  申请人：UNIV TEXAS

  公开号：WO2014160339A1

  公开（公告）日：2014-10-02

  Compounds are provided that can exhibit anti-cancer and/or anti-inflammatory properties, in some aspects, methods of treating an inflammatory disease or a hyperproliferative disease, such as cancer, with the compounds are provided.

  提供了一些化合物，可以展示抗癌和/或抗炎特性，在某些方面，提供了使用这些化合物治疗炎症性疾病或过度增殖性疾病（如癌症）的方法。
• Compounds for treating inflammatory and hyperproliferative diseases
  申请人：Board of Regents, The University of Texas System

  公开号：US10208012B2

  公开（公告）日：2019-02-19

  Compounds are provided that can exhibit anti-cancer and/or anti-inflammatory properties, in some aspects, methods of treating an inflammatory disease or a hyperproliferative disease, such as cancer, with the compounds are provided.

  所提供的化合物具有抗癌和/或抗炎特性，在某些方面，还提供了用这些化合物治疗炎症性疾病或过度增殖性疾病（如癌症）的方法。
• COMPOUNDS FOR TREATING INFLAMMATORY AND HYPERPROLIFERATIVE DISEASES
  申请人：BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM

  公开号：US20160016931A1

  公开（公告）日：2016-01-21

  Compounds are provided that can exhibit anti-cancer and/or anti-inflammatory properties, in some aspects, methods of treating an inflammatory disease or a hyperproliferative disease, such as cancer, with the compounds are provided.