2-(2'-tert-butyldimethylsiloxy)phenyl-3-methylbenzofuran | 148120-56-3

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 2-芳基苯并呋喃类黄酮
• 英文名称: 2-(2'-tert-butyldimethylsiloxy)phenyl-3-methylbenzofuran
• 英文别名: Tert-butyl-dimethyl-[2-(3-methyl-1-benzofuran-2-yl)phenoxy]silane
• CAS: 148120-56-3
• 化学式: C₂₁H₂₆O₂Si
• 分子量: 338.522
• InChiKey: CTRGGVIECDQNMK-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.79
• 重原子数：
  24
• 可旋转键数：
  4
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  22.4
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  2-(2'-tert-butyldimethylsiloxy)phenyl-3-methylbenzofuran 在 tetraphenylporphyrine 、 氧气 作用下， 以 二氯甲烷 为溶剂， 反应 7.0h， 以37%的产率得到2a,7b-dihydro-2a-(2'-tert-butyldimethylsiloxy)phenyl-7b-methyl-1,2-dioxeto<3,4-b>benzofuran
  参考文献：
  名称：

  Synthesis and fluoride ion - Triggered chemiluminescence (CIEEL mechanism) of siloxy-substituted benzofuran dioxetanes

  摘要：

  The dioxetanes 2 with tert-butyldimethylsilyoxy-substituted aryl groups have been prepared from the corresponding benzofurans by photooxygenation and their fluoride ion-triggered CIEEL chemiluminescence was investigated; facile saponification by fluoride and even phenoxide ions of the aryl esters 4 is held responsible for the low chemiluminescence efficiencies.

  DOI：

  10.1016/s0040-4020(01)80366-5
• 作为产物：
  描述：

  叔丁基二甲基氯硅烷 、 2-(3-methylbenzofuran-2-yl)phenol 在 咪唑 作用下， 以 二氯甲烷 为溶剂， 以87%的产率得到2-(2'-tert-butyldimethylsiloxy)phenyl-3-methylbenzofuran
  参考文献：
  名称：

  Synthesis and fluoride ion - Triggered chemiluminescence (CIEEL mechanism) of siloxy-substituted benzofuran dioxetanes

  摘要：

  The dioxetanes 2 with tert-butyldimethylsilyoxy-substituted aryl groups have been prepared from the corresponding benzofurans by photooxygenation and their fluoride ion-triggered CIEEL chemiluminescence was investigated; facile saponification by fluoride and even phenoxide ions of the aryl esters 4 is held responsible for the low chemiluminescence efficiencies.

  DOI：

  10.1016/s0040-4020(01)80366-5

文献信息

• Synthesis and fluoride ion - Triggered chemiluminescence (CIEEL mechanism) of siloxy-substituted benzofuran dioxetanes
  作者：Waldemar Adam、Rainer Fell、Manfred H. Schulz

  DOI：10.1016/s0040-4020(01)80366-5

  日期：1993.3

  The dioxetanes 2 with tert-butyldimethylsilyoxy-substituted aryl groups have been prepared from the corresponding benzofurans by photooxygenation and their fluoride ion-triggered CIEEL chemiluminescence was investigated; facile saponification by fluoride and even phenoxide ions of the aryl esters 4 is held responsible for the low chemiluminescence efficiencies.