(E)-icos-9-en-1-ol

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: (E)-icos-9-en-1-ol
• 化学式: C₂₀H₄₀O
• 分子量: 296.5
• InChiKey: DJYWKXYRGAMLRE-VAWYXSNFSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  8.5
• 重原子数：
  21
• 可旋转键数：
  17
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.9
• 拓扑面积：
  20.2
• 氢给体数：
  1
• 氢受体数：
  1

文献信息

• Lubricating oil composition
  申请人：IDEMITSU KOSAN COMPANY LIMITED

  公开号：EP0407977A1

  公开（公告）日：1991-01-16

  A lubricating oil composition comprising a major amount of at least one lubricating base oil, from 0.05 to 5 % by weight of at least one zinc dithiophosphate, and from 0.01 to 10 % by weight of at least one unsaturated aliphatic alcohol of from 16 to 24 carbon atoms, the weight ratio of the unsaturated aliphatic alcohol to the zinc dithiophosphate being from 0.1 to 10, has excellent thermostability and oxidation stability and has excellent effect in improving load carrying capacity and wear resistance.

  一种润滑油组合物，其主要成分包括至少一种润滑基础油、0.05%-5%（按重量计）的至少一种二硫代磷酸锌和 0.01%-10%（按重量计）的至少一种碳原子数为 16-24 的不饱和脂肪醇，其中不饱和脂肪醇与二硫代磷酸锌的重量比为 0.1-10，具有极佳的热稳定性和氧化稳定性，在提高承载能力和耐磨性方面效果显著。
• Additive for lubricating oil and lubricating oil composition containing said additive
  申请人：IDEMITSU KOSAN COMPANY LIMITED

  公开号：EP0475141A1

  公开（公告）日：1992-03-18

  Disclosed herein is an additive for lubricating oil which comprises a zinc dithiophosphate, a compound having at least one hydroxyl group and carbon-carbon double bond in a molecule thereof and cuprous oxide. Also disclosed herein a lubricating oil composition which comprises a base oil for lubricating oil and the above-mentioned additive for lubricating oil. The aforementioned additive is particularly effective for improving color change to black, sludge formation, stability a against oxidation and anti-wear property for zinc dithiophosphate (ZnDTP)-compounded lubricating oil composition.

  本文公开了一种润滑油添加剂，它由二硫代磷酸锌、其分子中至少有一个羟基和碳碳双键的化合物以及氧化亚铜组成。 本文还公开了一种润滑油组合物，它由润滑油基础油和上述润滑油添加剂组成。 上述添加剂对改善二硫代磷酸锌（ZnDTP）复配润滑油组合物的变黑、油泥形成、抗氧化稳定性和抗磨损性能特别有效。
• Formulations useful for the treatment of varicella zoster virus infections and methods for the use thereof
  申请人：Verbiscar J. Anthony

  公开号：US20050203187A1

  公开（公告）日：2005-09-15

  Jojoba alcohol, a mixture of long chain monounsaturated alcohols, is an oily liquid at moderate ambient temperatures. It is readily absorbed by human skin where it relieves irritation and inhibits the formation of lesions caused by viruses. The inhibitory action is applicable to enveloped viruses which express as sores at dermal surfaces in humans. When applied topically to an incipent herpes episode, it will quickly penetrate the epidermis to the subdermal vascular cells and suppress viral replication which leads to inflammation and the formation of blisters on the face, genital and other skin and mucosal areas. Fumaric acid and malonic acid at low concentrations also inhibit the replication of varicella zoster virus in human cell cultures, with no cellular toxicity. Compositions of certain low molecular weight organic acids in jojoba alcohol enhance antiviral activity. Topical treatment of shingles with a low concentration of fumaric acid in jojoba alcohol terminates the episode. This combination drug acts by a dual mechanism wherein the jojoba alcohol blocks viral fusion by a lipoidal mode, and the polycarboxylic acids inhibit viral fusion by an ionic mode. The combination drug can also be effective in treating chicken pox. Jojoba alcohol is a carrier and transdermal delivery system for these and other pharmacologically active agents for the relief of pain and treatment of other conditions which occur at or under the surface of the skin. Topically applied jojoba alcohol is non-toxic and safe for animals and humans.

  荷荷巴醇是一种长链单不饱和醇的混合物，在中等环境温度下呈油状液体。它很容易被人体皮肤吸收，从而缓解皮肤刺激，抑制病毒引起的病变的形成。这种抑制作用适用于在人体皮肤表面表现为溃疡的包膜病毒。在疱疹发作时局部使用，它能迅速穿透表皮到达皮下血管细胞，抑制病毒复制，从而导致面部、生殖器和其他皮肤及粘膜部位发炎并形成水疱。低浓度的富马酸和丙二酸也能抑制水痘带状疱疹病毒在人类细胞培养物中的复制，且对细胞无毒性。荷荷巴醇中的某些低分子量有机酸成分可增强抗病毒活性。用霍霍巴醇中的低浓度富马酸局部治疗带状疱疹，可终止带状疱疹的发作。这种复方药物通过双重机制发挥作用，荷荷巴醇类通过脂质模式阻断病毒融合，而多羧酸则通过离子模式抑制病毒融合。这种复方药物还能有效治疗水痘。荷荷巴醇是这些药物和其他药理活性剂的载体和透皮给药系统，可用于缓解疼痛和治疗发生在皮肤表面或皮下的其他病症。局部使用荷荷巴醇对动物和人类无毒、安全。
• FORMULATIONS USEFUL FOR THE TREATMENT OF VARICELLA ZOSTER VIRUS INFECTIONS AND METHODS FOR THE USE THEREOF
  申请人：Verbiscar, Anthony, J.

  公开号：EP1850670A1

  公开（公告）日：2007-11-07
• EP1850670A4
  申请人：——

  公开号：EP1850670A4

  公开（公告）日：2008-08-06