1,5-Hexanediol, 3-phenyl- | 1823902-99-3

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: 1,5-Hexanediol, 3-phenyl-
• 英文别名: 3-phenylhexane-1,5-diol
• CAS: 1823902-99-3
• 化学式: C₁₂H₁₈O₂
• 分子量: 194.27
• InChiKey: IVBVNVIJBRTZIH-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.8
• 重原子数：
  14
• 可旋转键数：
  5
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  40.5
• 氢给体数：
  2
• 氢受体数：
  2

文献信息

• Synthesis of [3,5,7]--1H-imidazo [1,5-a]imidazol-2 (3H)- one compounds
  申请人：——

  公开号：US20020193608A1

  公开（公告）日：2002-12-19

  Individual substituted [3,5,7]-1H-imidazo[1,5-a]imidazol-2(3H)-one compounds and their pharmaceutically-acceptable salts are disclosed, as are libraries of such compounds. Methods of preparing and using the libraries of compounds as well as individual compounds of the libraries are also disclosed.

  本发明公开了单个取代的[3,5,7]-1H-咪唑[1,5-a]咪唑-2(3H)-酮化合物及其药学上可接受的盐，以及此类化合物的化合物库。还公开了制备和使用化合物库以及化合物库中单个化合物的方法。
• Diketodiazacyclic compounds, diazacyclic compounds and combinatorial libraries thereof
  申请人：——

  公开号：US20030120066A1

  公开（公告）日：2003-06-26

  The synthesis of individual di- and tri-substituted-1,4-diazacyclic compounds having 6- to 8-atoms in the cyclic ring, their corresponding 1,6-diketo-2,5-diazacyclic compounds and similar 1,4-diazacyclic ring compounds having one ring carbonyl gorup and 6-8 atoms in the ring is disclosed, as are libraries of such compounds. Methods of preparing and using the libraries of compounds as well as individual compounds of the libraries are also disclosed.

  本发明公开了单个二取代和三取代-1,4-二氮杂环化合物的合成方法，这些化合物在环中具有 6 至 8 个原子，以及相应的 1,6-二酮-2,5-二氮杂环化合物和类似的 1,4-二氮杂环化合物，这些化合物在环中具有一个环羰基和 6 至 8 个原子。还公开了制备和使用化合物库以及化合物库中单个化合物的方法。
• 1,3,5- trisubstituted-1,3,5-triazine-2,4,6-trione compounds and libraries
  申请人：——

  公开号：US20030186320A1

  公开（公告）日：2003-10-02

  The solid-phase synthesis of individual 1,3-disubstituted and 1,3,5-trisubstituted-1,3,5-triazine-2,4,6-triones and libraries thereof from a resin is described. Reaction of resin-bound amino acids with isocyanates yields resin-bound ureas, which further react with chlorocarbonyl isocyanate to selectively afford the resin-bound 1,3-disubstituted-1,3,5-triazine-2,4,6-triones. Selective alkylation at the N-5 position of the resin-bound 1,3-disubstituted-1,3,5-triazine-2,4,6-triones produces a trisubstituted triazinetrione. The products are cleaved from their solid support and obtained in good yield and purity.

  介绍了从树脂中固相合成单个 1,3-二取代和 1,3,5-三取代-1,3,5-三嗪-2,4,6-三酮及其化合物库的方法。与树脂结合的氨基酸与异氰酸酯反应生成与树脂结合的脲，再与异氰酸氯羰基酯反应选择性地生成与树脂结合的 1,3-二取代-1,3,5-三嗪-2,4,6-三酮。在树脂结合的 1,3-二取代-1,3,5-三嗪-2,4,6-三酮的 N-5 位进行选择性烷基化，可生成三取代三嗪三酮。这些产物可从其固体支持物中裂解出来，产量和纯度都很高。
• SYNTHESIS OF 3,5,7|-1H-IMIDAZO 1,5-A|IMIDAZOL-2(3H)-ONE COMPOUNDS
  申请人：TORREY PINES INSTITUTE FOR MOLECULAR STUDIES

  公开号：EP1218337B1

  公开（公告）日：2007-10-31
• US5783577A
  申请人：——

  公开号：US5783577A

  公开（公告）日：1998-07-21