3t-(4-benzyl-phenyl)-acrylic acid | 99480-37-2

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 3t-(4-benzyl-phenyl)-acrylic acid
• 英文别名: 3t-(4-Benzyl-phenyl)-acrylsaeure；(E)-3-(4-benzylphenyl)prop-2-enoic acid
• CAS: 99480-37-2
• 化学式: C₁₆H₁₄O₂
• 分子量: 238.286
• InChiKey: RWDMMSKHSPIQER-ZHACJKMWSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.1
• 重原子数：
  18
• 可旋转键数：
  4
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.06
• 拓扑面积：
  37.3
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  3t-(4-benzyl-phenyl)-acrylic acid 在 溴 作用下， 生成 3-(4-benzyl-phenyl)-2,3-dibromo-propionic acid
  参考文献：
  名称：

  Gilbert, Journal des Recherches du Centre National de la Recherche Scientifique, 1956, vol. 7, p. 271,282

  摘要：

  DOI：
• 作为产物：
  描述：

  4-苄基苯甲醛 在 sodium acetate 、 乙酸酐 作用下， 生成 3t-(4-benzyl-phenyl)-acrylic acid
  参考文献：
  名称：

  Gilbert, Journal des Recherches du Centre National de la Recherche Scientifique, 1956, vol. 7, p. 271,281, 282

  摘要：

  DOI：

文献信息

• Propionic Acid Derivatives and Methods of Use Thereof
  申请人：Biediger Ronald J.

  公开号：US20180312498A1

  公开（公告）日：2018-11-01

  Provided herein are compounds and pharmaceutical compositions of formula I where R 1 , R 2 , R 3 , R 4 , R 5 , X and R 6 are as described herein. Also provided pharmaceutically acceptable salts or stereoisomer(s) of these compounds. In addition methods are provided for antagonizing the action of an α4-integrin to treat various pathophysiological conditions.

  本文提供了化合物和制药组合物的公式I，其中R1、R2、R3、R4、R5、X和R6如本文所述。还提供了这些化合物的药用可接受盐或立体异构体。此外，还提供了拮抗α4整合素作用以治疗各种病理生理条件的方法。
• ADHESIVE COMPOSITION INCLUDING AT LEAST TWO TYPES OF DYES, ADHESIVE SHEET, AND DISPLAY DEVICE INCLUDING SAME
  申请人：LMS Co., Ltd.

  公开号：US20200325363A1

  公开（公告）日：2020-10-15

  The present invention discloses a adhesive sheet effectively blocking light in the ultraviolet light region without deteriorating the transmittance with respect to the visible light region and the adhesiveness and a adhesive composition including binder resin and light absorption dye dispersed in the binder resin, and it is possible to effectively block light under the 410 nm wavelength region and to be applied to a various kinds of display devices.

  本发明揭示了一种粘合片，能够有效地阻挡紫外光区域的光线，而不会降低对可见光区域的透射率和粘附性，该粘合剂组合物包括分散在粘合树脂中的粘合剂树脂和光吸收染料，并且能够有效地阻挡410纳米波长区域的光线，并适用于各种显示设备。
• TETRACYCLIC INHIBITORS OF FATTY ACID AMIDE HYDROLASE
  申请人：Boger Dale L.

  公开号：US20100249078A1

  公开（公告）日：2010-09-30

  Certain tetracyclic compounds are described, which may be used in pharmaceutical compositions and methods for treating disease states, disorders, and conditions mediated by fatty acid amide hydrolase (FAAH) activity. Thus, the compounds may be administered to treat, e.g., anxiety, pain, inflammation, sleep disorders, eating disorders, or movement disorders (such as multiple sclerosis).

  本文描述了某些四环化合物，可用于制备药物组合物和方法，用于治疗由脂肪酸酰胺水解酶（FAAH）活性介导的疾病状态、障碍和病况。因此，这些化合物可以用于治疗焦虑、疼痛、炎症、睡眠障碍、进食障碍或运动障碍（例如多发性硬化）。
• Propionic acid derivatives and methods of use thereof
  申请人：Biediger Ronald J.

  公开号：US10246451B2

  公开（公告）日：2019-04-02

  Provided herein are compounds and pharmaceutical compositions of formula I where R1, R2, R3, R4, R5, X and R6 are as described herein. Also provided pharmaceutically acceptable salts or stereoisomer(s) of these compounds. In addition methods are provided for antagonizing the action of an α4-integrin to treat various pathophysiological conditions.

  本文提供了式 I 的化合物和药物组合物 其中 R1、R2、R3、R4、R5、X 和 R6 如本文所述。还提供了这些化合物的药学上可接受的盐或立体异构体。此外，还提供了拮抗α4-整合素作用以治疗各种病理生理状况的方法。
• ADHESIVE SHEET HAVING EXCELLENT ULTRAVIOLET BLOCKING FUNCTION, ADHESIVE COMPOSITION, AND DISPLAY DEVICE COMPRISING SAME
  申请人：LMS Co., Ltd.

  公开号：US20200216721A1

  公开（公告）日：2020-07-09

  The present invention discloses an adhesive sheet which effectively blocks light in a ultraviolet region without impairing the transmittance of light in a visible light region and adhesion, an adhesive composition comprising a binder resin, and a light absorbing dye dispersed in the binder resin, and the present invention can effectively block light in a wavelength range of 410 nm or less, and can be applied to various kinds of display devices.