Propan-2-yl 2-hydroxyoctadecanoate | 141718-98-1

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: Propan-2-yl 2-hydroxyoctadecanoate
• CAS: 141718-98-1
• 化学式: C₂₁H₄₂O₃
• 分子量: 342.6
• InChiKey: VSRNXEQNCICBHD-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  8.6
• 重原子数：
  24
• 可旋转键数：
  18
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.95
• 拓扑面积：
  46.5
• 氢给体数：
  1
• 氢受体数：
  3

文献信息

• UV ABSORBER FORMULATIONS
  申请人：Acker Stephanie

  公开号：US20100111884A1

  公开（公告）日：2010-05-06

  Disclosed is a UV filter composition comprising (a) an organic UV absorber of formula (1), wherein R 1 and R 2 , independently of one another, are C 3 -C 18 alkyl; C 2 -C 18 alkenyl; a radical of the formula —CH 2 —CH(OH)—CH 2 —O-T 1 ; or R 1 and R 2 are a radical of the formula (4a); R 7 is a direct bond; a straight-chain or branched C 1 -C 4 alkylene radical or a radical of the formula (I) or (II); R 8 , R 9 and R 10 , independently of one another, are C 1 -C 18 alkyl; C 1 -C 18 alkoxy or a radical of the formula (III); R 11 is C 1 -C 5 alkyl; m 1 is a number from 1 to 4; p 1 is 0; or a number from 1 to 5; A 1 is a radical of the formula (1b), (1c) or (1d); R 3 is hydrogen; C 1 -C 10 alkyl; —(CH 2 CHR 5 —O)n 1 -T 2 ; or —CH 2 —CH(—OH)—CH 2 —O-T 2 ; R 4 is hydrogen; M; C 1 -C 5 alkyl; or —(CH 2 )m 2 —O-T 3 ; R 5 is hydrogen; or methyl; T 1 , T 2 and T 3 independently from each other are hydrogen; or C 1 -C 18 alkyl; Q 1 is C 1 -C 18 alkyl, M is a metal cation; m 2 is 1 to 4; and n 1 is 1-16, (b) dimethyl capramide, (c) a cosmetically acceptable carrier; and water.

  本发明公开了一种紫外线过滤组合物，包括（a）式（1）的有机紫外线吸收剂，其中R1和R2独立地是C3-C18烷基；C2-C18烯基；式—CH2—CH（OH）— —O-T1的基团；或者R1和R2是式（4a）的基团；R7是直链或支链C1-C4烷基、式（I）或（II）的基团；R8、R9和R10独立地是C1-C18烷基、C1-C18烷氧基或式（III）的基团；R11是C1-C5烷基；m1是1至4的数字；p1是0或1至5的数字；A1是式（1b）、（1c）或（1d）的基团；R3是氢、C1-C10烷基、式—（ CHR5—O）n1-T2或式— —CH（—OH）— —O-T2；R4是氢、M、C1-C5烷基或式—（ ）m2—O-T3；R5是氢或甲基；T1、T2和T3互相独立地是氢或C1-C18烷基；Q1是C1-C18烷基，M是金属阳离子；m2是1至4的数字；n1是1-16，（b）二甲基辛酰胺，（c）化妆品可接受载体；和水。
• Linkage of agents using microparticles
  申请人：Green Howard

  公开号：US20060110379A1

  公开（公告）日：2006-05-25

  Methods, products and kits are provided for attaching agents to a skin surface via microparticles using endogenous or exogenous transglutaminase.

  提供了一种方法、产品和套件，可通过内源或外源性谷氨酰胺转移酶使用微粒子将药剂附着到皮肤表面。
• Lipstick composition
  申请人：KOLMAR LABORATORIES INC.

  公开号：EP0508591A2

  公开（公告）日：1992-10-14

  A lipstick composition comprising by weight from 8% to 20% of waxes, 30% to 80% of oils, 3% to 30% of colorants, 8% to 20% of cetearyl isononanoate, 1% to 10% of a sesquistearate and 2% to 20% of isopropyl hydroxystearate. The lipstick has the aesthetic performance characteristics of a regular lipstick but more effectively soothes and protects the lips.

  一种唇膏组合物，按重量计包括 8%至 20%的蜡、30%至 80%的油、3%至 30%的着色剂、8%至 20%的鲸蜡硬脂酰异壬酸酯、1%至 10%的倍半硬脂酸酯和 2%至 20%的羟基硬脂酸异丙酯。这种唇膏具有普通唇膏的美观特性，但能更有效地舒缓和保护嘴唇。
• Monohydric alcohol-free composition for topical use comprising solubilized ethylcellulose
  申请人：L'Oreal S.A.

  公开号：EP0861657A2

  公开（公告）日：1998-09-02

  A monohydric alcohol-free composition for topical use on human lips and skin. Said composition comprising a commercially acceptable carrier and solubilized ethylcellulose. The ethylcellulose being substantially solubilized in at least one solvent which may be a natural oil, triglyceride, propylene glycol ester, neopentyl glycol ester, fatty alcohol or mixtures thereof. The invention is advantageous in that the use of the above-described solvents in combination with ethylcellulose in a cosmetic or pharmaceutical composition enables effective amounts of ethylcellulose to more easily be solubilized into the cosmetic or pharmaceutical in the absence of alcoholic solvents, thereby forming improved formulations having enhanced durability and adhesion efficacies and that are more tolerable by the skin or lips, while advantageously avoiding the use of monohydric alcoholic solvents.

  一种不含一元醇的组合物，可局部用于人类嘴唇和皮肤。所述组合物包括商业上可接受的载体和增溶的乙基纤维素。乙基纤维素基本上溶解在至少一种溶剂中，这种溶剂可以是天然油、甘油三酯、丙二醇酯、新戊二醇酯、脂肪醇或它们的混合物。本发明的优点在于，在化妆品或药物组合物中结合使用上述溶剂与乙基纤维素，可使有效量的乙基纤维素在没有醇类溶剂的情况下更容易地溶解到化妆品或药物中，从而形成具有更高的耐久性和粘附效果的改良配方，并且更容易被皮肤或嘴唇耐受，同时有利地避免使用一元醇溶剂。
• Process for producing cosmetic and pharmaceutical formulations, and products comprising same
  申请人：Dragoco Gerberding & Co Aktiengesellschaft

  公开号：EP0974332A1

  公开（公告）日：2000-01-26

  Cosmetic or pharmaceutical formulations such as (a) anhydrous cosmetic stick formulations and (b) anhydrous aerosol spray formulations, comprising an organic dispersion medium having particles dispersed therein, which particles are preferably prepared by a process comprising spray-drying a mixture of liposome encapsulated active agent, modified starch, and optionally a hydrocolloid gum such as maltodextrin.

  化妆品或药物制剂，如 (a) 无水化妆品棒制剂和 (b) 无水气溶胶喷雾制剂，包括一种有机分散介质，其中分散有微粒，微粒最好是通过喷雾干燥脂质体包裹的活性剂、改性淀粉和可选的水胶体胶（如麦芽糊精）混合物的工艺制备而成。