N4-Cyclohexyl-N2-[(3-methoxyphenyl)methyl]-3,5-dimethyl-1H-pyrrole-2,4-dicarboxamide

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚醚
• 英文名称: N4-Cyclohexyl-N2-[(3-methoxyphenyl)methyl]-3,5-dimethyl-1H-pyrrole-2,4-dicarboxamide
• 英文别名: 4-N-cyclohexyl-2-N-[(3-methoxyphenyl)methyl]-3,5-dimethyl-1H-pyrrole-2,4-dicarboxamide
• 化学式: C₂₂H₂₉N₃O₃
• mdl: MFCD14797029
• 分子量: 383.5
• InChiKey: MMCRAZNVXVLLNG-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.6
• 重原子数：
  28
• 可旋转键数：
  6
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.45
• 拓扑面积：
  83.2
• 氢给体数：
  3
• 氢受体数：
  3

文献信息

• FLAVIVIRUS INHIBITORS AND METHODS FOR THEIR USE
  申请人：Padmanabhan Radhakrishnan

  公开号：US20110224207A1

  公开（公告）日：2011-09-15

  Methods of treating, preventing, and/or ameliorating a Flavivirus infection in a subject are disclosed. The methods comprise administering to the subject a therapeutically effective amount of a Flavivirus inhibitor, e.g., a Flavivirus serine protease inhibitor. These methods are useful in treating, preventing, and/or ameliorating Flavivurs infections such as, for example, West Nile Virus, Dengue Virus, and Japanese Encephalitis Virus.
• Flavivirus Inhibitors and Methods of Their Use
  申请人：Padmanabhan Radhakrishnan

  公开号：US20140038962A1

  公开（公告）日：2014-02-06

  Methods of treating, preventing, and/or ameliorating a Flavivirus infection in a subject are disclosed. The methods comprise administering to the subject a therapeutically effective amount of a Flavivirus inhibitor, e.g., a Flavivirus serine protease inhibitor. These methods are useful in treating, preventing, and/or ameliorating Flavivirus infections such as, for example, West Nile Virus, Dengue Virus, and Japanese Encephalitis Virus.
• US8563580B2
  申请人：——

  公开号：US8563580B2

  公开（公告）日：2013-10-22
• US8906937B2
  申请人：——

  公开号：US8906937B2

  公开（公告）日：2014-12-09