[4-(2-羟基苯甲酰基)苯基]-(2-羟基苯基)甲酮 | 66832-95-9

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 中文名称: [4-(2-羟基苯甲酰基)苯基]-(2-羟基苯基)甲酮
• 英文名称: 1,4-phenylenebis[(2-hydroxyphenyl)methanone]
• 英文别名: 1,4-disalicyloylbenzene；(1,4-Phenylene)bis[(2-hydroxyphenyl)methanone]；[4-(2-hydroxybenzoyl)phenyl]-(2-hydroxyphenyl)methanone
• CAS: 66832-95-9
• 化学式: C₂₀H₁₄O₄
• 分子量: 318.329
• InChiKey: YEMSWWWGIBCIEM-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.1
• 重原子数：
  24
• 可旋转键数：
  4
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  74.6
• 氢给体数：
  2
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  1,4-二碘苯 、 水杨醛 在 dicarbonylacetylacetonato rhodium (I) 、 碳酸氢钠 作用下， 以 N,N-二甲基甲酰胺 为溶剂， 反应 2.0h， 以91%的产率得到[4-(2-羟基苯甲酰基)苯基]-(2-羟基苯基)甲酮
  参考文献：
  名称：

  铑催化的定向基团辅助的芳基卤代甲烷CH-H芳基化反应

  摘要：

  建立了广泛的合成2'-取代的二苯甲酮的范围，涉及在铑催化的条件下，直接基团（OH或NHTs）辅助芳基醛与芳基卤化物的C–H芳基化。

  DOI：

  10.1002/ejoc.201700881

文献信息

• Bandyopadhyay, Chandrakanta; Sur, Kumar Ranabir; Das, Hemanta Kumar, Journal of Chemical Research, Miniprint, 1999, # 10, p. 2561 - 2568
  作者：Bandyopadhyay, Chandrakanta、Sur, Kumar Ranabir、Das, Hemanta Kumar

  DOI：——

  日期：——
• POLY(ETHER KETONE KETONE) POLYMERS, CORRESPONDING SYNTHESIS METHODS AND POLYMER COMPOSITIONS AND ARTICLES MADE THEREFROM
  申请人：SOLVAY SPECIALTY POLYMERS USA, LLC

  公开号：US20200087455A1

  公开（公告）日：2020-03-19

  Described herein are poly(ether ketone ketone) (“PEKK”) polymers having improved processability. It was surprisingly discovered that by selectively controlling the relative amounts of reactants during the synthesis, PEKK polymers having unexpectedly lower melt viscosities can be obtained. More particularly, by selectively controlling the relative amounts of monomers used to form recurring units of the PEKK polymer, in conjunction with selective control of other reaction components, the resulting PEKK polymers had reduced viscosities, relative to PEKK polymers synthesized by using tradition reaction schemes (“traditional PEKK polymers”). By providing PEKK polymers with lower melt viscosities, the PEKK polymers described herein have improved processability.
• Rhodium-Catalyzed Directing-Group-Assisted Aldehydic C-H Arylations with Aryl Halides
  作者：Maddali L. N. Rao、Boddu S. Ramakrishna

  DOI：10.1002/ejoc.201700881

  日期：2017.9.15

  A broad scope for the synthesis of 2′‐substituted benzophenones was established involving directing group (OH or NHTs) assisted C–H arylation of aryl aldehydes with aryl halides under rhodium‐catalyzed conditions.

  建立了广泛的合成2'-取代的二苯甲酮的范围，涉及在铑催化的条件下，直接基团（OH或NHTs）辅助芳基醛与芳基卤化物的C–H芳基化。