4-Hydroxybutyl octanoate | 256234-26-1

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: 4-Hydroxybutyl octanoate
• CAS: 256234-26-1
• 化学式: C₁₂H₂₄O₃
• 分子量: 216.32
• InChiKey: RETXUWFOZKDPPJ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.1
• 重原子数：
  15
• 可旋转键数：
  11
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.92
• 拓扑面积：
  46.5
• 氢给体数：
  1
• 氢受体数：
  3

文献信息

• Molecular Healing of Polymeric Materials, Coatings, Plastics, Elastomers, Composites, Laminates, Adhesives, and Sealants by Active Enzymes
  申请人：McDaniel C. Steven

  公开号：US20100210745A1

  公开（公告）日：2010-08-19

  Disclosed herein are polymeric materials such as a coating, a plastic, a laminate, a composite, an elastomer, an adhesive, or a sealant; a surface treatment such as a textile finish or a wax; a filler for such a polymeric material or a surface treatment that includes an enzyme such as an esterase (e.g., a lipolytic enzyme, a sulfuric ester hydrolase, an organophosphorus compound degradation enzyme), an enzyme (e.g., a lysozyme, a lytic transglycosylase) that degrades a cell wall and/or a cell membrane component, a biocidal or biostatic peotide, and/or a peptidase. Also disclosed herein are methods of altering a material's property such as service life, flexability, or rigidity, by incorporation of an enzyme into a material capable of being chemically crosslinked by the activity of a lipolytic enzyme, a hydrolase, and/or a urease.

  本文公开了一些聚合材料，如涂层、塑料、层压板、复合材料、弹性体、粘合剂或密封剂；一种表面处理，如纺织品涂层或蜡；一种填料，用于这样的聚合材料或表面处理，其中包括一种酶，如酯酶（例如，脂肪水解酶，硫酸酯水解酶，有机磷化合物降解酶），降解细胞壁和/或细胞膜成分的酶（例如，溶菌酶，裂解转糖基酶），生物杀菌或生物静态肽，以及/或肽酶。本文还公开了通过将酶纳入可通过脂肪水解酶、水解酶和/或脲酶的活性交联材料中来改变材料性能，如使用寿命、柔韧性或刚度的方法。
• Anti-fouling Paints and Coatings
  申请人：Reactive Surfaces LTD

  公开号：US20150191607A1

  公开（公告）日：2015-07-09

  Disclosed herein are polymeric materials such as a coating, a plastic, a laminate, a composite, an elastomer, an adhesive, or a sealant; a surface treatment such as a textile finish or a wax; a filler for such a polymeric material or a surface treatment that includes an enzyme such as an esterase (e.g., a lipolytic enzyme, a sulfuric ester hydrolase, an organophosphorus compound degradation enzyme), an enzyme (e.g., a lysozyme, a lytic transglycosylase) that degrades a cell wall and/or a cell membrane component, a biocidal or biostatic peptide, and/or a peptidase. Also disclosed herein are methods of altering a material's property such as service life, flexability, or rigidity, by incorporation of an enzyme into a material capable of being chemically crosslinked by the activity of a lipolytic enzyme, a hydrolase, and/or a urease.

  本文披露了聚合材料，例如涂层、塑料、层压材料、复合材料、弹性体、粘合剂或密封剂；表面处理，例如纺织品整理或蜡；填充剂，用于这种聚合材料或表面处理，包括酯酶（例如脂肪水解酶、硫酸酯水解酶、有机磷化合物降解酶）的酶，降解细胞壁和/或细胞膜成分的酶（例如溶菌酶、裂解转葡糖苷酶），生物杀菌或生物稳定肽，和/或肽酶。本文还披露了通过将酶并入能够通过脂肪水解酶、水解酶和/或脲酶的活性进行化学交联的材料中，改变材料性能（例如使用寿命、柔韧性或刚度）的方法。
• EXTERNAL PREPARATION CONTAINING CYCLOSPORIN
  申请人：LTT INSTITUTE CO., LTD.

  公开号：EP0547229A1

  公开（公告）日：1993-06-23

  An external preparation containing cyclosporin as the active ingredient, characterized by comprising (a) cyclosporin, (b) an organic solvent for dissolving the same, (c) a fatty acid ester of a monohydric alcohol, which is liquid at 25 °C and bears at least 8 carbon atoms in total, and/or an alkanolamine which is liquid at 25 °C, (d) an oleaginous substance which is solid at 25 °C, and (e) a surfactant, wherein the cyclosporin content ranges from 0.1 to 10 wt.% and the content of the ester and/or alkanolamine ranges from 1 to 15 wt.%. The preparation has an excellent efficacy of curing atopic dermatitis, psoriasis, allergic contact dermatitis, and so forth.

  一种含有环孢素作为有效成分的外用制剂，其特征在于包括：(a) 环孢素，(b) 用于溶解环孢素的有机溶剂，(c) 一元醇的脂肪酸酯，该脂肪酸酯在 25 °C时为液态，总共含有至少 8 个碳原子，和/或烷醇胺，该烷醇胺在 25 °C时为液态，(d) 含油物质，该含油物质在 25 °C时为固态，和 (e) 表面活性剂，其中环孢素的含量范围为 0.1 至 10 重量%，酯和/或烷醇胺的含量为 1 至 15 重量%。该制剂在治疗特应性皮炎、牛皮癣、过敏性接触性皮炎等方面具有极佳的疗效。
• Crosslinked oil droplet-based cosmetic or pharmaceutical emulsions
  申请人：Schreiber Jorg

  公开号：US20050106199A1

  公开（公告）日：2005-05-19

  The invention is a crosslinked water-in-oil emulsion that is useful in cosmetic and pharmaceutical applications. The emulsion includes a water phase, oil phase, water-in-oil emulsifier, and one or more crosslinkers. The crosslinkers that are useful in the invention include molecules having at least one hydrophilic region and at least one hydrophobic region. The invention also includes a process for preparing the crosslinked emulsion.

  本发明是一种交联油包水型乳液，可用于化妆品和医药应用。乳液包括水相、油相、油包水乳化剂和一种或多种交联剂。在本发明中有用的交联剂包括具有至少一个亲水区域和至少一个疏水区域的分子。本发明还包括制备交联乳液的工艺。
• Crosslinked cosmetic or pharmaceutical phospholipid-containing gels and emulsions based on ethylene oxide-containing or propylene oxide-containing emulsifiers
  申请人：Schreiber Jorg

  公开号：US20050142153A1

  公开（公告）日：2005-06-30

  The invention is a process for making a cosmetic or pharmaceutical, phospholipid-containing crosslinked microemulsion gel or crosslinked oil-in-water emulsion. The process includes the use of at least one crosslinker that is added to at least one of the water phase and the oil phase of the emulsion, or the is added after the water phase and oil phase are mixed.

  本发明是一种用于制造化妆品或药物、含磷脂交联微乳凝胶或交联水包油型乳液的工艺。该工艺包括使用至少一种交联剂，将其添加到乳液的水相和油相中的至少一个相中，或在水相和油相混合后添加。