Butyl 2-methylprop-2-enoate;2-hydroxyethyl 2-methylprop-2-enoate

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: Butyl 2-methylprop-2-enoate;2-hydroxyethyl 2-methylprop-2-enoate
• 化学式: C14H24O5
• 分子量: 272.34
• InChiKey: AHZHXMSESKAESX-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.0
• 重原子数：
  19
• 可旋转键数：
  9
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.57
• 拓扑面积：
  72.8
• 氢给体数：
  1
• 氢受体数：
  5

文献信息

• Polymeric compositions for controlled release or delivery of pharmacologically active agents
  申请人：Cordis Corporation

  公开号：EP1792966A2

  公开（公告）日：2007-06-06

  The present invention relates to polymeric compositions for controlled release or delivery of pharmacologically active agents. Each polymeric composition comprises a biocompatible polymeric matrix containing at least one pharmacologically active agent that is susceptible to oxidative degradation. The biocompatible polymeric matrix comprises at least a first polymeric material with an active antioxidant functional moiety covalently bound thereto in sufficient amount for protecting the at least one pharmacologically active agent against oxidative degradation. Optionally, the biocompatible polymeric matrix further comprises a second polymeric material that is essentially free of covalently bound active antioxidant functional moiety. The present invention also relates to a medical device that comprises an implantable structure, while at least a portion of the implantable structure either comprises or is coated with at least one of the above-described polymeric compositions.

  本发明涉及用于控制释放或输送药理活性剂的聚合物组合物。每种聚合物组合物都包括一种生物相容性聚合物基质，其中含有至少一种易氧化降解的药理活性剂。生物相容性聚合物基质至少包括第一种聚合物材料，其上共价结合有足够量的活性抗氧化官能团，可保护至少一种药理活性剂不被氧化降解。可选地，生物相容性聚合物基质还包括基本上不含共价结合的活性抗氧化剂官能团的第二种聚合物材料。本发明还涉及一种医疗设备，该设备包括一个可植入结构，而该可植入结构的至少一部分包括或涂覆有上述至少一种聚合物组合物。
• POLYMER COMPOUND AND PRODUCTION METHOD THEREOF, PIGMENT DISPERSING AGENT, PIGMENT DISPERSION COMPOSITION, PHOTOCURABLE COMPOSITION, AND COLOR FILTER AND PRODUCTION METHOD THEREOF
  申请人：FUJIFILM Corporation

  公开号：EP2006310A9

  公开（公告）日：2009-07-22

  The present invention provides a polymer compound represented by the following Formula (1) and a method for production thereof, a pigment dispersant, a pigment dispersion composition, and a photocurable composition respectively using the polymer compound, and a color filter and a method for production thereof [R1: an organic linking group having a valency of (m+n); R2: a single bond or a divalent organic linking group; A1: a monovalent organic group containing at least one moiety selected from an organic dye structure, a heterocyclic structure, an acidic group, a group having a basic nitrogen atom, a urea group, a urethane group, a group having a coordinating oxygen atom, a hydrocarbon group having 4 or more carbon atoms, an alkoxysilyl group, an epoxy group, an isocyanate group, and a hydroxyl group; m = 1 to 8, n = 2 to 9 (m+n = 3 to 10); and P1: polymer skeleton].

  本发明提供了由下式（1）表示的聚合物化合物及其生产方法，分别使用该聚合物化合物的颜料分散剂、颜料分散组合物和光硬化组合物，以及彩色滤光片及其生产方法[R1：价数为（m+n）的有机连接基团；R2：单键或二价有机连接基团；A1：含有至少一个分子的一价有机基团，这些分子选自有机染料结构、杂环结构、酸性基团、具有碱性氮原子的基团、脲基团、聚氨酯基团、具有配位氧原子的基团、具有 4 个或更多碳原子的烃基、烷氧基硅烷基团、环氧基团、异氰酸酯基团和羟基；m = 1 至 8，n = 2 至 9（m+n = 3 至 10）；以及 P1：聚合物骨架]。
• Angiogenic material and uses thereof
  申请人：——

  公开号：US20020037308A1

  公开（公告）日：2002-03-28

  An angiogenic material is disclosed which promotes extensive vascularization when implanted in animal tissue. The angiogenic material is preferably used in microcapsule coatings and microspheres for implantation in animals. In microcapsules, the angiogenic material promotes better exchange of nutrients, waste products and cellular products between encapsulated cells and the circulatory system of the host animal. Microspheres containing the angiogenic material may be used to assist in recovery of ischemic heart muscle by injection of the microspheres into the heart muscle or blood vessels serving the ischemic area. Also disclosed is a method of forming small microcapsules and microspheres by passing cell aggregates or air bubbles through layers of a density gradient.

  本发明公开了一种血管生成材料，植入动物组织后可促进广泛的血管生成。这种血管生成材料最好用于植入动物体内的微胶囊涂层和微球中。在微胶囊中，血管生成材料可促进封装细胞与宿主动物循环系统之间更好地交换营养物质、废物和细胞产物。将含有血管生成材料的微球注射到缺血区域的心肌或血管中，可用于帮助缺血心肌的恢复。还公开了一种通过细胞聚集体或气泡通过密度梯度层形成小微囊和微球的方法。
• MEDICAL DEVICE COMPRISING RESVERATROL FUNCTIONALIZED POLYMERIC COATING
  申请人：Cordis Corporation

  公开号：EP1792966B1

  公开（公告）日：2017-06-28
• Method of making a coated container device
  申请人：Dow Global Technologies LLC

  公开号：EP2456679B2

  公开（公告）日：2020-08-19