O-(4-(trifluoromethoxy)benzyl)hydroxylamine | 535975-99-6

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚醚
• 英文名称: O-(4-(trifluoromethoxy)benzyl)hydroxylamine
• 英文别名: O-[[4-(trifluoromethoxy)phenyl]methyl]hydroxylamine
• CAS: 535975-99-6
• 化学式: C₈H₈F₃NO₂
• 分子量: 207.15
• InChiKey: PUGCUCFAELENTA-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2
• 重原子数：
  14
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.25
• 拓扑面积：
  44.5
• 氢给体数：
  1
• 氢受体数：
  6

文献信息

• [EN] POLYHALOGENATED PROPENE BENZOQUINONE DIOXIME DERIVATIVES AND ITS USE AS PESTICIDES<br/>[FR] DERIVES DE PROPENE-BENZOQUINONE-DIOXIME POLYHALOGENES ET LEUR UTILISATION EN TANT QUE PESTICIDES
  申请人：BAYER CROPSCIENCE AG

  公开号：WO2006037496A1

  公开（公告）日：2006-04-13

  Novel dihalogenopropene derivatives of the formula (I) and of the formula (Ia), wherein A, A1, A2, G, Q, R1, R2, R3, R4, and X have the meaning provided in the description, Methods and intermediates for their production as well as their use for combattiing pests.

  具有以下公式(I)和公式(Ia)的新型二卤代丙烯衍生物，其中A、A1、A2、G、Q、R1、R2、R3、R4和X的含义如描述中所提供的含义，以及它们的生产方法和中间体，以及它们用于对抗害虫的用途。
• Novel Hydroxamic Acid Esters and Pharmaceutical Use Thereof
  申请人：Fensholdt Jef

  公开号：US20070244117A1

  公开（公告）日：2007-10-18

  The invention relates to compounds of general formula I wherein D, E, F, G, W, Y, R 1 , A, R 9 , X, B, R 8 are as defined herein, and pharmaceutically acceptable salts, hydrates, or solvates thereof, for use—alone or in combination with one or more other pharmaceutically active compounds—in therapy, for treating diseases associated with deregulated angiogenesis, such as cancer.

  本发明涉及一般式I的化合物，其中D、E、F、G、W、Y、R1、A、R9、X、B、R8如本文所定义，并且其药学上可接受的盐、水合物或溶剂化物，用于治疗与异常血管生成相关的疾病，如癌症，可单独使用或与一个或多个其他药理活性化合物联合使用。
• PROCESS FOR PRODUCTION OF COLLECTION COLUMNS FOR CARBONYL COMPOUNDS
  申请人：SUMIKA CHEMICAL ANALYSIS SERVICE, LTD.

  公开号：EP1431760A1

  公开（公告）日：2004-06-23

  There is provided a method for producing a sampling tube for carbonyl compound, manifesting low blank value and enabling analysis of carbonyl compounds such as formaldehyde and the like in air or in water with high sensitivity and high accuracy by a simple manner, which comprises the following steps: contacting a cation exchanger packed in a tube with a hydrophilic solvent or a mixed solvent containing this; contacting the cation exchanger contacted with a hydrophilic solvent or a mixed solvent containing this with a solution of a compound of the following structural formula (1): [in the formula, R1, R2, R3, R4 and R5 each independently represent a hydrogen atom, halogen atom, alkyl group, haloalkyl group, alkoxyl group, haloalkoxyl group, aryl group or haloaryl group, and R6 and R7 represent a hydrogen atom or alkyl group (wherein, when R6 and R7 represent a hydrogen atom, at least one of R1, R2, R3, R4 and R5 is not a fluorine atom)] or a salt thereof, to allow the cation exchanger to support the compound; and washing the cation exchanger supporting the compound with a hydrophilic solvent or a mixed solvent containing this two or more times.

  本发明提供了一种用于生产羰基化合物采样管的方法，这种采样管空白值低，能以简单的方式对空气或水中的甲醛等羰基化合物进行高灵敏度和高精确度的分析，该方法包括以下步骤： 将装在管中的阳离子交换器与亲水性溶剂或含有亲水性溶剂的混合溶剂接触； 将与亲水性溶剂或含有亲水性溶剂的混合溶剂接触的阳离子交换器与下列结构式 (1) 的化合物溶液接触： [式中，R1、R2、R3、R4 和 R5 各自独立地代表氢原子、卤素原子、烷基、卤代烷基、烷氧基、卤代烷氧基、芳基或卤代芳基，R6 和 R7 代表氢原子或烷基（其中，当 R6 和 R7 代表氢原子时，R1、R2、R3、R4 和 R5 中至少有一个不是氟原子）]或其盐，以使阳离子交换剂支持该化合物；以及 用亲水性溶剂或含有亲水性溶剂的混合溶剂洗涤支撑化合物的阳离子交换剂两次或两次以上。
• Process for production of collection columns for carbonyl compounds
  申请人：——

  公开号：US20040248313A1

  公开（公告）日：2004-12-09

  There is provided a method for producing a sampling tube for carbonyl compound, manifesting low blank value and enabling analysis of carbonyl compounds such as formaldehyde and the like in air or in water with high sensitivity and high accuracy by a simple manner, which comprises the following steps: contacting a cation exchanger packed in a tube with a hydrophilic solvent or a mixed solvent containing this; contacting the cation exchanger contacted with a hydrophilic solvent or a mixed solvent containing this with a solution of a compound of the following structural formula (1): 1 [in the formula, R 1 , R 2 , R 3 , R 4 and R 5 each independently represent a hydrogen atom, halogen atom, alkyl group, haloalkyl group, alkoxyl group, haloalkoxyl group, aryl group or haloaryl group, and R 6 and R 7 represent a hydrogen atom or alkyl group (wherein, when R 6 and R 7 represent a hydrogen atom, at least one of R 1 , R 2 , R 3 , R 4 and R 5 is not a fluorine atom)] or a salt thereof, to allow the cation exchanger to support the compound; and washing the cation exchanger supporting the compound with a hydrophilic solvent or a mixed solvent containing this two or more times.

  本发明提供了一种用于生产羰基化合物采样管的方法，该采样管空白值低，能以简单的方式对空气或水中的甲醛等羰基化合物进行高灵敏度和高精度的分析，该方法包括以下步骤： 将装在管中的阳离子交换器与亲水性溶剂或含有亲水性溶剂的混合溶剂接触； 将与亲水性溶剂或含有亲水性溶剂的混合溶剂接触的阳离子交换器与下列结构式（1）的化合物溶液接触： 1 式中，R 1 , R 2 , R 3 , R 4 和 R 5 各自独立地代表氢原子、卤素原子、烷基、卤代烷基、烷氧基、卤代烷氧基、芳基或卤代芳基，以及 R 6 6 和 R 7 代表氢原子或烷基（其中，当 R 6 和 R 7 代表氢原子时，R 1 , R 2 , R 3 , R 4 和 R 5 或其盐，使阳离子交换剂能够支持该化合物；以及 用亲水性溶剂或含有亲水性溶剂的混合溶剂洗涤支撑化合物的阳离子交换剂两次或两次以上。
• HYDROXAMIC ACID ESTERS AND PHARMACEUTICAL USE THEREOF
  申请人：LEO PHARMA A/S

  公开号：EP1697312B1

  公开（公告）日：2011-07-20