7,9,11-Dodecatrien-1-ol, formate, (7Z,9E)- | 146321-32-6

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: 7,9,11-Dodecatrien-1-ol, formate, (7Z,9E)-
• 英文别名: [(7Z,9E)-dodeca-7,9,11-trienyl] formate
• CAS: 146321-32-6
• 化学式: C₁₃H₂₀O₂
• 分子量: 208.3
• InChiKey: OLTJQTSXVRBFPO-ICWBMWKASA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.3
• 重原子数：
  15
• 可旋转键数：
  10
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.46
• 拓扑面积：
  26.3
• 氢给体数：
  0
• 氢受体数：
  2

文献信息

• [EN] MODIFICATION OF SEXUAL BEHAVIOUR IN ANIMALS AND PEST CONTROL<br/>[FR] MODIFICATION DU COMPORTEMENT SEXUEL DES ANIMAUX ET LUTTE ANTIPARASITAIRE
  申请人：HORTICULTURE AND FOOD RESEARCH

  公开号：WO2000059545A1

  公开（公告）日：2000-10-12

  This invention comprises methods of modifying sexual behaviour in animals, and of use of these methods in pest control. The methods of the invention involve disrupting the function of a pheromone recognition area of the brain of an animal, specifically the vomeronasal organ (VNO). Compositions useful in the methods of the invention and are also provided. Compositions of the invention comprise antibody-cytotoxin and pheromone-cytotoxin conjugates. Useful cytotoxins include ricin A chain and domoic acid. Useful pheromones include those structurally related to dodecyl acetate including dodecyl acetate itself and (Z)-7-dodecen-1-yl acetate. Useful antibodies include monoclonal antibodies raised to the NMDAR1 sub-chain of the NMDA (N-methyl-D-aspartate) glutamate receptor which is present on the VNO.