[(R)-[(2S,4S,5R)-5-ethyl-1-azabicyclo[2.2.2]octan-2-yl]-(6-methoxyquinolin-4-yl)methyl] 2,3-dihydroindole-1-carboxylate | 192431-04-2

• 分子结构分类: 有机化合物 - 生物碱及其衍生物 - 金鸡纳生物碱
• 英文名称: [(R)-[(2S,4S,5R)-5-ethyl-1-azabicyclo[2.2.2]octan-2-yl]-(6-methoxyquinolin-4-yl)methyl] 2,3-dihydroindole-1-carboxylate
• CAS: 192431-04-2
• 化学式: C₂₉H₃₃N₃O₃
• 分子量: 471.6
• InChiKey: UNHDMQIPBRPXIA-PIFGEPKESA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.3
• 重原子数：
  35
• 可旋转键数：
  6
• 环数：
  7.0
• sp3杂化的碳原子比例：
  0.45
• 拓扑面积：
  54.9
• 氢给体数：
  0
• 氢受体数：
  5

文献信息

• SYNTHETIC LIPOPHILIC INOSITOL GLYCANS FOR TREATMENT OF CANCER AND GLUCOSE-METABOLISM DISORDERS
  申请人：D'alarcao Marc

  公开号：US20100197625A1

  公开（公告）日：2010-08-05

  The present intervention related to materials and methods for the synthesis of lipophilic inositol glycan compounds, and salts, solvates and physiological functional derivatives thereof, and their use for the treatment of cancer and glucose-metabolism disorders, such as, for example, diabetes, obesity and metabolic syndrome.