| 7320-45-8

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• CAS: 7320-45-8
• 化学式: C8H14NaO7S
• 分子量: 277.25
• InChiKey: BCVZNCWCAQBFPQ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.62
• 重原子数：
  17
• 可旋转键数：
  8
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.75
• 拓扑面积：
  115
• 氢给体数：
  1
• 氢受体数：
  7

文献信息

• [EN] PHARMACEUTICAL COMPOSITIONS OF SELECTIVE ANDROGEN RECEPTOR MODULATORS AND METHODS OF USE THEREOF<br/>[FR] COMPOSITIONS PHARMACEUTIQUES DE MODULATEURS SÉLECTIFS DES RÉCEPTEURS DES ANDROGÈNES ET LEURS PROCÉDÉS D'UTILISATION
  申请人：GTX INC

  公开号：WO2013067170A1

  公开（公告）日：2013-05-10

  This invention provides a pharmaceutical composition comprising Compound I-V, including inter alia solid dosage forms of powder-filled capsule formulations, liquid-filled softgel capsules (softgels), tablets, and sustained release dosage forms, and uses thereof in treating a variety of diseases or conditions in a subject, for example, treating a muscle wasting disease and/or disorder, a bone related disease and/or disorder, metabolic syndrome, diabetes and associated diseases, and others.

  这项发明提供了一种包含化合物I-V的药物组合物，包括固体剂型的填粉胶囊制剂、液体填充软胶囊（软胶囊）、片剂和缓释剂型，以及在治疗受试者中各种疾病或症状中的用途，例如治疗肌肉消耗疾病和/或紊乱、骨相关疾病和/或紊乱、代谢综合征、糖尿病及相关疾病等。
• Polymers containing poly(hydroxyalkanoates) and agents for use with medical articles and methods of fabricating the same
  申请人：Hossainy F.A. Syed

  公开号：US20060147412A1

  公开（公告）日：2006-07-06

  Polymers containing poly(hydroxyalkanoates) and agents for use with medical articles and methods of fabricating the same are disclosed. The medical article generally comprises an implantable substrate having a coating, and the coating contains a poly(hydroxyalkanoate).

  本发明公开了含有聚羟基烷酸酯的高分子以及用于医疗器械的制剂和制备方法。医疗器械通常包括具有涂层的可植入基质，而涂层含有聚羟基烷酸酯。
• Salts of fenofibric acid and pharmaceutical formulations thereof
  申请人：Cink Drew Russell

  公开号：US20050148594A1

  公开（公告）日：2005-07-07

  In one aspect, the present invention relates to a formulation in the form of molecular dispersion comprising i) fenofibric acid, a physiologically acceptable salt or derivative thereof and optionally other active substances, ii) a binder component comprising at least one enteric binder, and optionally iii) other physiologically acceptable excipients. In a second aspect, the present invention relates to novel salts of fenofibric acid that are photostable when compared to other salts of fenofibric acid.

  在一个方面，本发明涉及一种分子分散型制剂，其中包括i）芬非布酸，其生理上可接受的盐或衍生物，以及可选的其他活性物质，ii）至少包括一种肠溶性粘合剂的粘合剂组分，以及可选的iii）其他生理上可接受的辅料。在第二个方面，本发明涉及芬非布酸的新盐，与其他芬非布酸盐相比具有光稳定性。
• Salts of Fenofibric Acid and Pharmaceutical Formulations Thereof
  申请人：Cink Drew Russell

  公开号：US20080051411A1

  公开（公告）日：2008-02-28

  In one aspect, the present invention relates to a formulation in the form of molecular dispersion comprising i) fenofibric acid, a physiologically acceptable salt or derivative thereof and optionally other active substances, ii) a binder component comprising at least one enteric binder, and optionally iii) other physiologically acceptable excipients. In a second aspect, the present invention relates to novel salts of fenofibric acid that are photostable when compared to other salts of fenofibric acid.

  在一个方面，本发明涉及一种以分子分散形式的配方，包括i) 芬诺酸、其生理上可接受的盐或衍生物，以及可选的其他活性物质，ii) 至少包括一种肠溶性粘结剂的粘结剂组分，以及可选的iii) 其他生理上可接受的辅料。在第二个方面，本发明涉及芬诺酸的新型盐，与其他芬诺酸盐相比具有光稳定性。
• SALTS OF FENOFIBRIC ACID AND PHARMACEUTICAL FORMULATIONS THEREOF
  申请人：Cink Russell D.

  公开号：US20090263477A1

  公开（公告）日：2009-10-22

  In one aspect, the present invention relates to a formulation in the form of molecular dispersion comprising i) fenofibric acid, a physiologically acceptable salt or derivative thereof and optionally other active substances, ii) a binder component comprising at least one enteric binder, and optionally iii) other physiologically acceptable excipients. In a second aspect, the present invention relates to novel salts of fenofibric acid that are photostable when compared to other salts of fenofibric acid.

  在一个方面，本发明涉及一种以分子分散形式的制剂，包括i）非诺贝酸，其生理上可接受的盐或衍生物以及可选的其他活性物质，ii）包括至少一种肠溶性粘合剂的粘合剂组分，以及可选的iii）其他生理上可接受的辅料。在第二方面，本发明涉及非诺贝酸的新盐，与其他非诺贝酸盐相比具有光稳定性。