N~2~-(Methoxycarbonyl)-N,N-dimethylglycinamide | 84004-73-9

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: N~2~-(Methoxycarbonyl)-N,N-dimethylglycinamide
• 英文别名: methyl N-[2-(dimethylamino)-2-oxoethyl]carbamate
• CAS: 84004-73-9
• 化学式: C₆H₁₂N₂O₃
• 分子量: 160.17
• InChiKey: GVJXGKLGFONDEA-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.5
• 重原子数：
  11
• 可旋转键数：
  3
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.666
• 拓扑面积：
  58.6
• 氢给体数：
  1
• 氢受体数：
  3

文献信息

• PROCESS FOR PRODUCTION OF OPTICALLY ACTIVE PIPERIDINE COMPOUND
  申请人：Mitsubishi Tanabe Pharma Corporation

  公开号：EP2022782A1

  公开（公告）日：2009-02-11

  The present invention relates to a method for preparing a syn-form piperidine compound represented by general formula [I]: wherein, bold lines represent bonds in which substituents at positions 2 and 4 of a piperidine ring are in the syn configuration, and the other symbols have the same meaning as defined below, or a salt thereof, comprising: reducing a compound represented by general formula [II]: wherein, ring A represents an optionally substituted benzene ring, R2 represents a hydrogen atom, an optionally substituted hydroxyl group, an optionally substituted amino group, an optionally substituted alkyl group, a substituted carbonyl group or a halogen atom, and M represents an alkaline metal or hydrogen atom.

  本发明涉及一种制备由通用式[I]表示的同构吡啶化合物的方法：其中，粗线表示吡啶环的2位和4位取代基处于同构构象，其他符号的含义如下定义，或其盐，包括：还原由通用式[II]表示的化合物：其中，环A表示一个可选择取代的苯环，R2表示氢原子、可选择取代的羟基、可选择取代的氨基、可选择取代的烷基、取代的羰基或卤素原子，M表示碱金属或氢原子。
• METHOD FOR PREPARING OPTICALLY ACTIVE PIPERIDINE COMPOUNDS
  申请人：Matsumae Hiroaki

  公开号：US20090198052A1

  公开（公告）日：2009-08-06

  The present invention relates to a method for preparing a syn-form piperidine compound represented by general formula [I]: wherein, bold lines represent bonds in which substituents at positions 2 and 4 of a piperidine ring are in the syn configuration, and the other symbols have the same meaning as defined below, or a salt thereof, comprising: reducing a compound represented by general formula [II]: wherein, ring A represents an optionally substituted benzene ring, R 2 represents a hydrogen atom, an optionally substituted hydroxyl group, an optionally substituted amino group, an optionally substituted alkyl group, a substituted carbonyl group or a halogen atom, and M represents an alkaline metal or hydrogen atom.

  本发明涉及一种制备一种由通式[I]表示的syn型哌啶化合物的方法：其中，粗线表示哌啶环的2和4位取代基处为syn构型，其他符号的含义如下所定义，或其盐，包括：还原由通式[II]表示的化合物：其中，环A表示可选取代的苯环，R2表示氢原子、可选取代的羟基、可选取代的氨基、可选取代的烷基、取代的羰基或卤素原子，M表示碱金属或氢原子。
• US7619092B2
  申请人：——

  公开号：US7619092B2

  公开（公告）日：2009-11-17