2,3-Dicyanopyrrol | 59175-49-4

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡咯
• 英文名称: 2,3-Dicyanopyrrol
• 英文别名: pyrrole-2,3-dicarbonitrile；1H-Pyrrole-2,3-dicarbonitrile
• CAS: 59175-49-4
• 化学式: C₆H₃N₃
• mdl: MFCD19221243
• 分子量: 117.11
• InChiKey: SWIRXXWZEVGZSC-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.5
• 重原子数：
  9
• 可旋转键数：
  0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  63.4
• 氢给体数：
  1
• 氢受体数：
  2

文献信息

• Pyrrolo[2,1-F] [1,2,4] Triazin-4-Ylamines IGF-1R Kinase Inhibitors for the Treatment of Cancer and Other Hyperproliferative Diseases
  申请人：O'Connor Stephen

  公开号：US20110294776A1

  公开（公告）日：2011-12-01

  This invention relates to novel compounds of formula (I). Formula (I) in which the variable groups are as defined in the specification and claims, to pharmaceutical compositions containing them, and to a method of treatment using them for treatment of cancer.

  本发明涉及公式（I）的新化合物。公式（I）中变量基团如规范和要求中所定义，以及含有它们的制药组合物和使用它们治疗癌症的治疗方法。
• 2-ACYLAMINOTHIAZOLE DERIVATIVE OR SALT THEREOF
  申请人：Sugasawa Keizo

  公开号：US20100222329A1

  公开（公告）日：2010-09-02

  A 2-acylaminothiazole derivative or a pharmaceutically acceptable salt thereof having an excellent effect of proliferating human c-mpl-Ba/F3 cells and an activity of increasing platelets based on the effect of promoting the formation of megakaryocytic colonies. A compound or a pharmaceutically acceptable salt thereof useful in treating thrombocytopenia.

  一种2-酰氨基噻唑衍生物或其药学上可接受的盐，具有促进人类c-mpl-Ba/F3细胞增殖的优异效果，并且基于促进巨核细胞集落形成的作用而具有增加血小板活性。该化合物或其药学上可接受的盐可用于治疗血小板减少症。
• Pyrrole carbonitrile and nitro-pyrrole insecticidal, acaricidal and molluscicidal agents and methods for the preparation thereof
  申请人：AMERICAN CYANAMID COMPANY

  公开号：EP0372263A2

  公开（公告）日：1990-06-13

  There are provided certain insecticidal, acaricidal and molluscicidal pyrrole carbonitrile and nitropyrrole compounds and a method for controlling insects, acarids and mollusks therewith. The invention also provides a method for protecting growing plants from insect, acarid and mollusk attack by applying to said plants or the soil or water in which they are growing, an insecticidally, acaricidally or molluscici­dally effective amount of a pyrrole carbonitrile or nitropyrrole compound. The present invention further relates to methods for the preparation of said pyrrole carbonitrile and nitropyrrole compounds.

  本发明提供了某些杀虫、杀螨虫和杀软体动物的吡咯腈和硝基吡咯化合物，以及用其控制昆虫、螨虫和软体动物的方法。本发明还提供了一种保护生长中的植物免受昆虫、螨虫和软体动物攻击的方法，即向上述植物或其生长的土壤或水中施用杀虫、杀螨或杀软体动物有效量的吡咯腈或硝基吡咯化合物。本发明还涉及制备所述吡咯腈和硝基吡咯化合物的方法。
• Methods and compositions for protecting animals against attack and infestation by helminth, acarid and anthropod endo- and ectoparasites
  申请人：AMERICAN CYANAMID COMPANY

  公开号：EP0557732A1

  公开（公告）日：1993-09-01

  This invention relates to methods and compositions for treating, controlling, preventing and protecting warm-blooded animals from infestation and infection by helminths, acarids and arthropod endo- and ectoparasites by administering or applying to the animals a nitropyrrole or pyrrole carbonitrile compound.

  本发明涉及通过向动物施用或应用硝基吡咯或吡咯腈化合物来治疗、控制、预防和保护温血动物免受蠕虫、螨虫和节肢动物内寄生虫和外寄生虫侵扰和感染的方法和组合物。
• Intermediates useful for the synthesis of pesticides
  申请人：RHONE-POULENC AGROCHIMIE

  公开号：EP0708090A1

  公开（公告）日：1996-04-24

  The present invention pertains to novel 3-substituted-4-thiopyrrole intermediates for the preparation of 1-arylpyrrole compounds that are useful for the control of insects, acarids and nematodes. The compounds, including their isomers, e.g., diastereomers and optical isomers, are compounds of a general formula (I) wherein R, R₁, R₂, W and n are as defined in the description.

  本发明涉及用于制备 1-芳基吡咯化合物的新型 3-取代-4-巯基吡咯中间体，这些化合物可用于防治昆虫、害虫和线虫。 这些化合物，包括它们的异构体，例如非对映异构体和光学异构体，是通式（I）的化合物 其中 R、R₁、R₂、W 和 n 如说明中所定义。