n-丙基二硫代乙酸 | 136852-81-8

• 分子结构分类: 有机化合物 - 有机硫化合物 - 有机二硫化物
• 中文名称: n-丙基二硫代乙酸
• 英文名称: n-propyldithioacetic acid
• 英文别名: 2-(Propyldisulfanyl)acetic acid
• CAS: 136852-81-8
• 化学式: C₅H₁₀O₂S₂
• 分子量: 166.265
• InChiKey: FTTYNGWAXWEYIQ-UHFFFAOYSA-N

物化性质

• 沸点：
  275.1±23.0 °C(Predicted)
• 密度：
  1.244±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  1.4
• 重原子数：
  9
• 可旋转键数：
  5
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.8
• 拓扑面积：
  87.9
• 氢给体数：
  1
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  2-n-propyldithiopyridine-N-oxide 、 巯基乙酸 以 氯仿 为溶剂， 反应 23.0h， 以100%的产率得到n-丙基二硫代乙酸
  参考文献：
  名称：

  Synthesis of disulfides via sulfenylation of alkyl and aryldithiopyridine n-oxides

  摘要：

  Alkyl and aryldithiopyridine N-oxides were prepared by the reaction of 2,2'-dithiopyridine-1,1'-dioxide with various thiols in high yields. Some of the mixed disulfide products could in turn be used to sulfenylate efficiently other thiols. Therefore, practical and efficient synthetic methods for both symmetrical and unsymmetrical disulfides were developed.

  DOI：

  10.1016/s0040-4020(01)86546-7

文献信息

• Synthesis of disulfides via sulfenylation of alkyl and aryldithiopyridine n-oxides
  作者：Derek H.R. Barton、Chen Chen、G. Michael Wall

  DOI：10.1016/s0040-4020(01)86546-7

  日期：1991.8

  Alkyl and aryldithiopyridine N-oxides were prepared by the reaction of 2,2'-dithiopyridine-1,1'-dioxide with various thiols in high yields. Some of the mixed disulfide products could in turn be used to sulfenylate efficiently other thiols. Therefore, practical and efficient synthetic methods for both symmetrical and unsymmetrical disulfides were developed.