S-[2-[3-[[(2R)-4-[[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-4-hydroxy-3-phosphonooxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl]oxy-2-hydroxy-3,3-dimethylbutanoyl]amino]propanoylamino]ethyl] propanethioate;2-oxopropanoic acid

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: S-[2-[3-[[(2R)-4-[[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-4-hydroxy-3-phosphonooxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl]oxy-2-hydroxy-3,3-dimethylbutanoyl]amino]propanoylamino]ethyl] propanethioate;2-oxopropanoic acid
• 化学式: C27H44N7O20P3S
• 分子量: 911.7
• InChiKey: ITJXGGYFZUWHDK-IEQRABFGSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -1.27
• 重原子数：
  58
• 可旋转键数：
  22
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.63
• 拓扑面积：
  443
• 氢给体数：
  10
• 氢受体数：
  25

文献信息

• [EN] MODIFIED MICROORGANISMS AND METHODS OF USING SAME FOR PRODUCING ISOPRENE, 2-METHYL-1-BUTANOL, 2-METHYL-1,3-BUTANEDIOL, AND/OR 2-METHYLBUT-2-EN-1-OL<br/>[FR] MICRO-ORGANISMES MODIFIÉS ET PROCÉDÉS D'UTILISATION DE CEUX-CI POUR PRODUIRE DE L'ISOPRÈNE, DU 2-MÉTHYL-1-BUTANOL, DU 2-MÉTHYL-1,3-BUTANEDIOL, ET/OU DU 2-MÉTHYL-BUT-2-ÉN-1-OL
  申请人：BRASKEM S A AP 09

  公开号：WO2014099927A1

  公开（公告）日：2014-06-26

  The present disclosure generally relates to microorganisms (e.g., non-naturally occurring microorganisms) that comprise one or more polynucleotides coding for enzymes in a pathway that catalyze a conversion of a carbon source (e.g., a fermentable carbon source) to isoprene, 2-methyl-1-butanol, 2-methyl-1,3-butanediol, and/or 2-methylbut-2-en-1-ol and the use of such microorganisms for the production of isoprene, 2-methyl-1-butanol, 2-methyl-1,3-butanediol, and/or 2-methylbut-2-en-1-ol.